Commercial plant-produced recombinant protein products : case studies
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書誌事項
Commercial plant-produced recombinant protein products : case studies
(Biotechnology in agriculture and forestry, v. 68)
Springer, c2014
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Attention has recently turned to using plants as hosts for the production of commercially important proteins. The twelve case studies in this volume present successful strategies for using plants to produce industrial and pharmaceutical proteins and vaccine antigens. They examine in detail projects that have commercial potential or products that have already been commercialized, illustrating the advantages that plants offer over bacterial, fungal or animal cell-culture hosts. There are many indications that plant protein production marks the beginning of a new paradigm for the commercial production of proteins that, over the next decade, will expand dramatically.
目次
1 Introduction - Plant-produced protein products
Elizabeth E. Hood and Paul Christou
Part I: Highly Purified Proteins
2 Commercial Plant-Produced Recombinant Avidin
Elizabeth E. Hood and John A. Howard
3 Molecular farming in plants - the long road to the market
Rainer Fischer, Johannes F Buyel, Stefan Schillberg and Richard M Twyman
4 TrypZean (TM): an animal-free alternative to bovine trypsin
Aparna Krishnan, Susan L. Woodard
5 Production of Pharmaceutical Grade Recombinant Native Aprotinin and Non-Oxidized Aprotinin-Variants Under Greenhouse and Field Conditions
Gregory P. Pogue, Fakhrieh Vojdani, Kenneth E. Palmer, Earl White, Hugh Haydon, Barry Bratcher
Part II: Vaccines
6 Influenza virus-like particles produced in Nicotiana benthamiana protect against a lethal viral challenge in mice
Louis-P Vezina, Brian J Ward, Marc-Andre D'Aoust, Manon Couture, Sonia Trepanier, Andrew Sheldon1, Nathalie Landry
7 Plant-Produced Recombinant Transmission Blocking Vaccine Candidates to Combat Malaria
Stephen J. Streatfield, Natasha Kushnir, Vidadi Yusibov
8 An oral vaccine for TGEV immunization of pigs
Rajan, V.
9 Edible Rabies Vaccines
Elizabeth Loza-Rubio and Edith Rojas-Anaya
10 Newcastle disease vaccines
Miguel A. Gomez Lim
11 An oral vaccine for hepatitis B: challenges, setbacks, and breakthroughs
Celine A. Hayden
Part III: Industrial Proteins
12 Commercial Plant-Produced Recombinant Cellulases for Biomass Conversion
Elizabeth E. Hood, Deborah V. Requesens
13 Brazzein: A High Intensity Natural Sweetener
Gina Fake and John Howard
Part IV: Future Directions
14 The Future of Plant-Produced Pharmaceuticals and Industrial Proteins
John Howard, Elizabeth E. Hood
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