A pharmacology primer : techniques for more effective and strategic drug discovery
著者
書誌事項
A pharmacology primer : techniques for more effective and strategic drug discovery
Elsevier, c2014
4th ed
大学図書館所蔵 件 / 全4件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references and index
内容説明・目次
内容説明
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research.
目次
Chapter 1 - What is Pharmacology?Chapter 2 - How Different Tissues Process Drug ResponseChapter 3 - Drug Receptor TheoryChapter 4 - Pharmacological Assay Formats: BindingChapter 5 - Agonists: The Measurement of Affinity and Efficacy in Functional AssaysChapter 6 - Orthosteric Drug AntagonismChapter 7 - Allosteric Drug InteractionsChapter 8 - Drug DiscoveryChapter 9 - Drug Development: Pharmacokinetics and Safety PharmacologyChapter 10 - Target-and System-based Strategies for Drug DiscoveryChapter 11 - Lead Optimization: Data-Driven AnalysisChapter 12 - Statistics and Experimental DesignChapter 13 - Selected Pharmacological MethodsChapter 14 - Exercises in Pharmacodynamics and PharmacokineticsGlossary of Pharmacological TermsAppendicesStatistical TablesMathematical Fitting Functions
「Nielsen BookData」 より