書誌事項

Amyotrophic lateral sclerosis

edited by Hiroshi Mitsumoto, Serge Przedborski, Paul H. Gordon

(Neurological disease and therapy)

Taylor & Francis, 2006

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注記

Includes bibliographical references and index

HTTP:URL=http://www.loc.gov/catdir/enhancements/fy0648/2005053812-d.html Information=Publisher description

収録内容

  • History of ALS
  • Epidemiology of ALS
  • The pathology of amyotrophic lateral sclerosis
  • The causes of sporadic amyotrophic lateral sclerosis
  • ALS clinical motor signs and symptoms
  • Frontotemporal dysfunction in amyotrophic lateral sclerosis
  • Familial ALS and genetic approaches to ALS
  • Objective markers of upper and lower motor neuron dysfunction: electrophysiological studies and neuroimaging technologies
  • Classification, diagnosis, and presentation of diagnosis of ALS
  • Natural history and prognosis in amyotrophic lateral sclerosis
  • Specifying motor identity in the developing spinal cord
  • Neurodegeneration in amyotrophic lateral sclerosis
  • Excitotoxicity
  • Superoxide dismutase, oxidative stress, and ALS
  • Neuronal and non-neuronal cell interactions in ALS
  • Apoptosis in amyotrophic lateral sclerosis
  • Cytoskeletal proteins in the pathogenesis of ALS
  • Role of mitochondria in motor neuron degeneration in ALS
  • Environmental toxicity and ALS: novel insights from an animal model of ALS-PDC
  • Genetic causes and predisposition
  • ALS: a protein aggregate disease?
  • Neuroinflammation
  • The potential of gene therapy for motor neuron diseases
  • Experimental models of motor neuron diseases
  • Screening for ALS drugs
  • Clinical trial methodology
  • The multidisciplinary care clinic: the principles and an international perspective
  • The ALS patient CARE program - North American patient CARE database
  • Symptomatic pharmacotherapy: bulbar and constitutional symptoms
  • ALS pharmacotherapy: riluzole and clinical trials
  • Rehabilitation
  • Nutritional treatment: theoretical and practical issues
  • Respiratory care in amyotrophic lateral sclerosis
  • Psychosocial care for patients with ALS and their caregivers
  • Palliative care at the end of life
  • Palliative care: family perspective
  • End-of-life decision making

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