Influenza pathogenesis and control

著者

• Compans, Richard W.
• Oldstone, Michael B. A.

書誌事項

Influenza pathogenesis and control

Richard W. Compans, Michael B.A. Oldstone, editors

（Current topics in microbiology and immunology, 385-386）

Springer, c2014-c2015

• v. 1
• v. 2

注記

Includes bibliographical references and index

内容説明・目次

巻冊次

v. 1 ISBN 9783319111544

内容説明

This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.

目次

Part I: Molecular determinants of pathogenicity The Hemagglutinin - a Determinant of Pathogenicity Eva Boettcher-Friebertshauser, Wolfgang Garten, Mikhail Matrosovich, and Hans Dieter Klenk Molecular determinants of pathogenicity in the polymerase complex Gulsah Gabriel and Ervin Fodor Part II: Virus entry and cell tropism Receptor binding properties of the influenza virus hemagglutinin as a determinant of host range Xiaoli Xiong, John W. McCauley, David A. Steinhauer Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology Charles J. Russell Part III: Transmission and Pandemics Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT) Nancy J. Cox, Susan C. Trock and Stephen A. Burke Avian influenza virus transmission to mammals S. Herfst, M. Imai, Y. Kawaoka and R.A.M. Fouchier Transmission in the Guinea Pig Model Anice C. Lowen, Nicole M. Bouvier and John Steel Enhancement of influenza virus transmission by gene reassortment Chengjun Li and Hualan Chen Swine and Influenza: A Challenge to One Health Research Robert E. Kahn, Wenjun Ma and Jurgen A. Richt Part IV: Animal models and pathogenesis Influenza Pathobiology and Pathogenesis in Avian Species Monique S. Fran a and Justin D. Brown Molecular determinants of influenza virus pathogenesis in mice Ram P. Kamal, Jaqueline M. Katz, and Ian A. York Mammalian models for the study of H7 virus pathogenesis and transmission Jessica A. Belser and Terrence M. Tumpey Pathogenesis and vaccination of influenza A virus in swine Daniela S. Rajao, Tavis K. Anderson, Phillip C. Gauger, Amy L. Vincent Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis Amber M. Smith and Jonathan A. McCullers Part V: Evolution, Antigenic Variation Evolution and Ecology of Influenza A viruses Sun-Woo Yoon, Richard J. Webby and Robert G. Webster Influenza A virus reassortment John Steel and Anice C. Lowen Antigenic Analyses of Highly Pathogenic Avian Influenza A Viruses Ruben O Donis

巻冊次

v. 2 ISBN 9783319111575

内容説明

This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.

目次

Part I: Innate immunity The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options John R. Teijaro Innate immune sensing and response to influenza Mohan S. Maddur and Bali Pulendran The NS1 protein: a multitasking virulence factor Juan Ayllon and Adolfo Garcia-Sastre Role of NK cells in influenza infection Stacey Shultz-Cherry Host detection and the stealthy phenotype in influenza virus infection Pradyot Dash and Paul G. Thomas Part II: Vaccines and adaptive immunity Inactivated and adjuvanted influenza vaccines Giuseppe Del Giudice and Rino Rappuoli Live attenuated influenza vaccine Hong Jin and Kanta Subbarao Design of alternative live attenuated influenza virus vaccines Courtney Finch, Weizhong Li and Daniel R. Perez Rapid production of synthetic influenza vaccines Philip R. Dormitzer Influenza neuraminidase as a vaccine antigen Maryna C. Eichelberger and Hongquan Wan Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin Florian Krammer, Peter Palese and John Steel Structural characterization of epitopes recognized by broadly cross-reactive antibodies Peter S. Lee and Ian A. Wilson Skin immunization with influenza vaccines Ioanna Skountzou and Richard W. Compans Mucosal immunization and adjuvants Hideki Hasegawa, Elly van Reit and Hiroshi Kida B cell responses to infection and vaccination Christopher Chiu, Ali Ellebedy, Jens Wrammert and Rafi Ahmed Memory CD4 T cells in influenza Kyra D. Zens and Donna L. Farber The effector T cell response to influenza infection Matthew M. Hufford, Taeg S. Kim, Jie Sun and Thomas J. Braciale Part III: New antiviral discovery Antiviral Effects of Inhibiting Host Gene Expression Ralph A. Tripp and S. Mark Tompkins

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BB17284129
• ISBN:
  • 9783319111544
  • 9783319111575
• 出版国コード: sz
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Cham
• ページ数/冊数: v.
• 大きさ: 25 cm
• 分類:
  • LCC : RC150
  • LCC : QR1
  • DC23 : 616.203
• 件名:
  • LCSH : Influenza
  • LCSH : Influenza -- Pathogenesis
  • LCSH : Influenza -- Prevention
• 親書誌ID:
  • BA00773360