Patient-reported outcomes : measurement, implementation and interpretation
著者
書誌事項
Patient-reported outcomes : measurement, implementation and interpretation
（Chapman & Hall/CRC biostatistics series）（A Chapman & Hall book）
CRC Press, c2014
- : hardback
- タイトル別名
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Patient reported outcomes : measurement, implementation and interpretation
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注記
Other authors: Kelly H. Zou, Andrew G. Bushmakin, Jose Ma. J. Alvir, Demissie Alemayehu, Tara Symonds
Includes bibliographical references and index
内容説明・目次
内容説明
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures.
The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The authors include many relevant real-life applications based on their extensive first-hand experiences in the pharmaceutical industry. They implement a wealth of simulated datasets to illustrate concepts and heighten understanding based on practical scenarios. For readers interested in conducting statistical analyses of PRO measures and delving more deeply into the analytic details, most chapters contain SAS code and output that illustrate the methodology. Along with providing numerous references, the book highlights current regulatory guidelines.
目次
Introduction. Development of a Patient-Reported Outcome. Validity. Reliability. Exploratory and Confirmatory Factor Analyses. Item Response Theory. Cross-Sectional Analysis. Longitudinal Analysis. Mediation Models. Missing Data. Enriching Interpretation. Index.
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