Handbook of H+-ATPases
著者
書誌事項
Handbook of H+-ATPases
Pan Stanford Publishing, 2014
- : hardcover
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling, in addition to describing the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, as well as under diabetic conditions.
目次
Vacuolar H+-ATPase Assembly. Structure of Prokaryotic V type ATPase/synthase. The function of V-ATPase in the degradation of gluconeogenic enzymes in the yeast vacuole. The Role of Vacuolar ATPase in the Regulation of Npt2a Trafficking. Cytosolic pH regulated by glucose promotes V-ATPase assembly. Vacuolar H+-ATPase (V-ATPase) activated by glucose, a possible link to diabetic disease. Vacuolar proton pump (V-ATPase) and insulin secretion. Role of V-ATPase, cytohesin-2/Arf6 and aldolase in regulation of endocytosis: Implications for diabetic nephropathy. Renal Vacuolar H+-ATPase Regulation. Long-term Regulation of Vacuolar H+-ATPase by Angiotensin II in Proximal Tubule Cells. Vacuolar H+-ATPase in Distal Renal Tubular Acidosis and Diabetes. Vacuolar H+-ATPase in Cancer and Diabetes. The a2 isoform of Vacuolar ATPase and Cancer-Related Inflammation. V-ATPases in oral squamous cell carcinoma. Vacuolar H(+)-ATPase : functional mechanism and potential as a target for cancer chemotherapy. Vacuolar H+-ATPase Maintains Neural Stem Cells in the Developing Mouse Cortex. The relationship between glucose-induced calcium signaling and activation of the plasma membrane H+-ATPase in Saccharomyces cerevisiae cells.
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