Biological basis of alcohol-induced cancer
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書誌事項
Biological basis of alcohol-induced cancer
（Advances in experimental medicine and biology, 815）
Springer, c2015
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
In the recent years, a significant amount of research has emerged connecting the link between alcohol and cancer. The field has rapidly advanced, especially since the complex connection between alcohol and cancer has several unique sub areas that are being investigated. This proceedings volume will contain chapters based upon the presentation of the 2nd International Conference on Alcohol and Cancer in Colorado, 2013. The various topics explore the affects of alcohol on: liver and breast cancer; cell signaling and cancer; stem cells; biomarkers and metabolomics; aerodigestive cancers; cancer and the immune system and more.
目次
Chapter 1: Introduction
Chapter 2: Alcohol and breast cancer: Reconciling epidemiological and molecular data
Chapter 3: Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking
Chapter 4: Alcohol and Cancer: an Overview With special Emphasis on the Role of Acetaldehyde and Cytochrome P-4502E1
Chapter 5: Implications of acetaldehyde-derived DNA adducts for understanding alcohol related carcinogenesis
Chapter 6: The role of iron in alcohol-mediated hepatocarcinogenesis
Chapter 7: Alcoholic Cirrhosis and Hepatocellular Carcinoma
Chapter 8: TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis
Chapter 9: Synergistic Toxic Interactions Between CYP2E1, LPS/TNF and JNK/p38 MAP Kinase and their Implications in Alcohol-induced Liver Injury
Chapter 10: Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma
Chapter 11: Alcohol consumption, Wnt/ -catenin signaling and hepatocarcinogensis
Chapter 12: Alcohol and HCV: Implications for Liver Cancer
Chapter 13: Application of Mass Spectrometry-based Metabolomics in Identification of Early Noninvasive Biomarkers of Alcohol-Induced Liver Disease Using Mouse Model
Chapter 14: Alcohol Metabolism by Oral Streptococci and Interaction with Human Papillomavirus Leads to Malignant Transformation of Oral Keratinocytes
Chapter 15: Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers
Chapter 16: Acetaldehyde and Retinaldehyde-Metabolizing Enzymes in Colon and Pancreatic cancers
Chapter 17: Alcohol, Carcinoembryonic Antigen Processing and Colorectal Liver Metastases
Chapter 18: Alcohol Consumption and Antitumor Immunity: Dynamic Changes from Activation to Accelerated Deterioration of the Immune System
Chapter 19: A Perspective on Chemoprevention by Resveratrol in Head and Neck Squamous Cell Carcinoma
Chapter 20: The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis
Chapter 21: The effect of alcohol on sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC)
Chapter 22: Transgenic Mouse Models for Alcohol Metabolism, Toxicity and Cancer
Chapter 23: Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate gland
Chapter 24: Fetal Alcohol Exposure and Mammary Tumorigenesis in Offspring: Role of the Estrogen and Insulin-like Growth Factor Systems
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