Zinc signals in cellular functions and disorders
著者
書誌事項
Zinc signals in cellular functions and disorders
Springer, c2014
大学図書館所蔵 全4件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book describes the crucial role of "zinc signals" in biological processes on a molecular and physiological basis, discussing future directions and questions underlying this unique phenomenon. To accomplish this, a group of worldwide leaders in the field, who have made outstanding contributions, overview zinc signals from a professional standpoint. Zinc plays an indispensable role in various cellular processes. It regulates a great number of protein functions including transcription factors, enzymes, adapters, and growth factors as a structural or catalytic factor or both. Recently, another function of zinc has received extensive interest and attention because of its potential importance as a signaling mediator. Zinc plays a dynamic role as an intracellular and extracellular signaling factor and thus regulates cellular signaling pathways, which enables communication between cells, conversion of extracellular stimuli to intracellular signals, and control of various intracellular events. These functions of zinc have become recognized as "zinc signals," which play critical roles in physiology, and therefore their imbalance can cause a variety of problems with regard to human health. Because the notion of zinc signals is quite new and no integrative review books focusing on them have yet been published, we believe this book will provide very timely information on the subject and thus should be of importance and interest to a wide range of readers.
目次
Foreword.- Preface.- 1 Introduction - "Zinc Signaling": The Blossoming Field of Zinc Biology (Taiho Kambe).- 2 Molecular Aspects of Zinc Signals (Wolfgang Maret).- 3 Zinc Transport Proteins and Zinc Signaling (Taiho Kambe, Tokuji Tsuji, and Kazuhisa Fukue).- 4 Oxidative Stress and Neuronal Zinc Signaling (Hirokazu Hara and Elias Aizenman).- 5 Zinc Signaling by "Zinc Wave" (Keigo Nishida and Satoru Yamasaki).- 6 The Zinc Sensing Receptor, ZnR/GPR39: Signaling and Significance (Michal Hershfinkel).- 7 Genetically-Encoded Fluorescent Probes for Intracellular Zn2+ Imaging (Anne M. Hessels and Maarten Merkx).- 8 Zinc Signal in Brain Functions (Atsushi Takeda).- 9 The Clinical Implications of Impaired Zinc Signalling in the Brain (Sara M. Hancock, Ashley I. Bush, and Paul A. Adlard).- 10 Zinc Signals in Immunology (Lothar Rink and Martina Maywald).- 11 Zinc Signal in Inflammation (Ming-Jie Liu and Daren L. Knoell).- 12 Zinc Signal in Growth Control and Bone Diseases (Toshiyuki Fukada, Shintaro Hojyo, and Bum-Ho Bin).- 13 Zinc and its Role in the Pathogenesis of Type 2 Diabetes (Yoshio Fujitani, Motoyuki Tamaki, Ayako Fukunaka, and Hirotaka Watada).- 14 Zinc Signalling and Cancer (Thirayost Nimmanon and Kathryn M. Taylor).- 15 Zinc as a Key Meiotic Cell Cycle Regulator in the Mammalian Oocyte (Ru Ya, Emily Que, Thomas V. O'Halloran, and Teresa K. Woodruff).- BM Future Perspectives (Toshiyuki Fukada).- Index.
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