WTEC panel on tissue engineering research : final report, January 2002
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Bibliographic Information
WTEC panel on tissue engineering research : final report, January 2002
Academic Press, c2003
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Tissue engineering research
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Includes bibliographical references
Description and Table of Contents
Description
WTEC Panel on Tissue Engineering Research is a comparative review of tissue engineering research and development activities in the United States, Japan, and Western Europe conducted by a panel of leading U.S. experts in the field. This book covers biomaterials, cells, biomolecules, non-medical applications, engineering design, informatics, and legal and regulatory issues associated with tissue engineering research and applications. This document will serve as a basis for continued dialogue within nations' tissue engineering research and development community and with other important stakeholders, providing guidance for future programs. This text highlights the necessity for providing continued and enhanced resources to further the progress in tissue engineering, harness developments, and maintain scientific and economic leadership.
Table of Contents
Foreword List of Figures List of TablesExecutive Summary1. Introduction Background: The Significance of Tissue Engineering History of Tissue Engineering Promise of Tissue Engineering Other Applications Emerging Industry of Tissue Engineering Objectives of the WTEC Study Scope and Methodology Vision for the Future Acknowledgements References 2 Biomaterials Introduction U.S. R&D Activities Japanese R&D Activities European R&D Activities Summary References 3 Cells Introduction Analysis of Current State of the Art and Factors Influencing Progress Control of Cell Proliferation and Differentiation U.S. R&D Activities Background Current Efforts Future Position R&D Activities in Europe Japan Summary References4 Biomolecules Introduction Gene Transfer Angiogenic Factors/Growth Factors Differentiation Factors Bone Morphogenic Proteins References 5 Cell-Based Technologies: Non-Medical Applications Introduction Overview of R&D Activities Summary 6 Engineering Design Aspects of Tissue Engineering Introduction Bioreactor Technology Preservation of Cells and Engineered Tissues Mass Transport Issues Following Implantation Biomechanics Issues Summary References 7 Informatics and Tissue Engineering Introduction Informatics Components That Will Ultimately Support Tissue Engineering U.S. R&D Activities European R&D Activities Japanese R&D Activities Summary References 8 Legal and Regulatory Issues Introduction FDA Regulation Other Considerations Relevant to Engineered Tissues Regulation of Pharmaceutical/Medical Human Tissue Products in Europe Regulation of Pharmaceutical/Medical Human Tissue Products in Japan Conclusion ReferencesAppendices A. Biographies of Panelists B. Site Reports-Europe bwA, Aachen Centre of Competence: Biomaterials Cell Lining GmbH Berlin Workshop ERA Consulting (UK), Ltd ETH Zurich European Agency for the Evaluation of Medicinal Products (EMEA) European Molecular Biology Laboratory (EMBL) German Cancer Research Center (DKFZ) German Heart Institute Humboldt University of Berlin, Charite Biomaterial and Tissue Repair Laboratory (INSERM) Imperial College of Science, Technology and Medicine Imperial College of Science, Technology and Medicine University of Glasgow IsoTis (Technical Report) IsoTis (Regulatory Report) Kirchhoff Institute of Physics (KIP) Manchester University Max Planck Institute for Polymer Research MeVis Smith & Nephew Group Research Centre University of Freiburg University of Koln University of Regensburg University of Twente C. Appendix C. Site Reports-Japan Hokkaido University Japan Tissue Engineering Company, Ltd Keio University Kyoto University Kyushu University Nippon Telegraph and Telephone Corporation (NTT) Basic Research Laboratories Nagoya University National Cancer Center Research Institute National Institute for Advanced Interdisciplinary Research (NAIR) National Institute of Bioscience and Human Technology Institute of Physical and Chemical Research (RIKEN) Cell Bank Tokyo Institute of Technology Tokyo Women's Medical University University of Tokyo University of Tsukuba D. Summary of the June 2000 U.S. Review Workshop E. The Federal Investment in Tissue Engineering
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