Clinical trials : a practical approach
Author(s)
Bibliographic Information
Clinical trials : a practical approach
John Wiley & Sons, c1983
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Note
Includes index
Description and Table of Contents
Description
This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author's personal experience.
Table of Contents
Introduction: The Rationale of Clinical Trials.
The Historical Development of Clinical Trials.
Organization and Planning.
The Justificaton for Randomized Controlled Trials.
Methods of Randomization.
Blinding and Placebos.
Ethical Issues.
Crossover Trials.
The Size of a Clinical Trial.
Monitoring Trial Progress.
Forms and Data Management.
Protocol Deviations.
Basic Principles of Statistical Analysis.
Further Aspects of Data Analysis.
Publication and Interpretation of Findings.
References.
Index.
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