New developments on signal transduction research
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Bibliographic Information
New developments on signal transduction research
（Cell biology research progress series）（Nova biomedical）
Nova Biomedical, c2013
- : hardcover
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Note
Includes bibliographical references and index
"Copyright c2013 by Nova Science Publishers,Inc" -- t.p.verso
"Nova biomedical"--cover
Description and Table of Contents
Description
Signal transduction plays a pivotal role in cell regulation. Hormones, cytokines and neurotransmitters bind to their specific receptors in the plasma membranes of cells. The receptors of many hormones are coupled to G-protein coupled signalling pathways. Insulin and growth factors are coupled to receptor-linked kinase. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. Cyclic adenosine monophosphate (cyclic AMP), inositol 1,3,5-triphosphate (IP3) and calcium ion (Ca2+) have been demonstrated to play a role as a second messenger in cells. The pivotal role of Ca2+ in cellular regulation was established with the finding of calmodulin and protein kinase C that modulates the effect of Ca2+ in the regulation of cellular functions. Many receptor classes and their downstream kinases activate Erk, Akt, Stat, Smad, NF- B and other cascades to regulate gene expression and cellular function. This book provides recent research in the study of the new developments in signalling transduction in cells.
Table of Contents
- Signal Transduction Mediated via Extracellular Calmodulin & Extracellular Calmodulin Binding Proteins
- Kinase Coupled Receptors & G-Protein Coupled Receptors Regulate Neural Stem Cell Differentiation via Common Signaling Pathways: Emerging Evidence for Convergent Regulation
- Pheromone Biosynthesis Activating Neuropeptide Receptors (PBANRs) in Moths: New Developments Regarding Alternative Splice Variants & the Potential for Targeted Disruption of PBANR in Pest Control
- Cdk5 Acts as a Surveillance System in the Nervous System
- The Role of Signal Transduction in Abnormal Embryonic Development
- Regucalcin, a Suppressor Protein in Signal Transduction
- Isolation & Partial Characterization of Reactive Oxygen Species (ROS) Resistant Mutants with High Yielding in Oryza sativa cv Koshihikari
- Index.
by "Nielsen BookData"