Signal transduction

Bibliographic Information

Signal transduction

IJsbrand M. Kramer

Elsevier Academic Press, c2016

3rd ed

Available at  / 20 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor - ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.

Table of Contents

  • 1. Prologue: Signal Transduction from a Historical Perspective2. An Introduction to Signal Transduction3. Regulation of Muscle Contraction by Receptors4. Cholinergic Signaling and Muscle Contraction5. Sensory Signal Processing
  • Visual Transduction and Olfaction6. Intracellular Calcium7. Bringing the Signal into the Nucleus: Regulation of Gene Expression8. Nuclear Receptors9. Protein Kinase C and Oncogenic Transformation and Cell Polarity10. Regulation of Cell Proliferation by Receptor Tyrosine Protein Kinases11. Signal Transduction to and from Adhesion Molecules12. WNT Signaling and the Regulation of Cell Adhesion and Differentiation13. Activation of the Innate Immune System: the Toll-Like Receptor-4 and Signaling through Ubiquitylation14. Chemokines and Traffic of White Blood Cells15. Activating the Adaptive Immune System: Role of Non-receptor Tyrosine Kinases16. Signaling through the Insulin Receptor: Phosphoinositide 3-Kinases and AKT17. TGFss and Signaling through Receptor Serine/Threonine Protein Kinases18. Protein Phosphates19. Cell Fate Determination by Notch

by "Nielsen BookData"

Details

  • NCID
    BB20151972
  • ISBN
    • 9780123948038
  • Country Code
    ne
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Amsterdam ; Tokyo
  • Pages/Volumes
    xlv, 1078 p.
  • Size
    24 cm
  • Classification
  • Subject Headings
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