Epigenomics in health and disease

Author(s)
    • Fraga, Mario
    • Fernández, Agustín
Bibliographic Information

Epigenomics in health and disease

edited by Mario Fraga, Agustín Fernández

(Translational epigenetics series)

Academic Press, an imprint of Elsevier, c2016

  • : hbk

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Description and Table of Contents

Description

Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.

Table of Contents

Preface 1. The Role of the Genetic Code in the DNA Methylation Landscape Formation 2. DNA Methylation Microarrays 3. Ultra Deep Sequencing of Bisulfite Modified DNA 4. Bioinformatics Tools in Epigenomic Studies 5. Genome-Wide DNA Methylation Changes During Aging 6. The Dynamics of Histone Modifications During Aging 7. The DNA Methylomes of Cancer 8. Non-coding RNA Regulation of Health and Disease 9. Genome-Wide Epigenetic Studies in Neurological Diseases 10. Epigenetic Deregulation in Autoimmune Disease 11. Genome-Wide DNA and Histone Modification Studies in Metabolic Disease 12. Epigenomic Studies in Epidemiology 13. Clinical Applications of Epigenomics

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