The cell : a molecular approach

Bibliographic Information

The cell : a molecular approach

Geoffrey M. Cooper, Robert E. Hausman

Sinauer Associates, c2016

7th ed

  • : [International ed]

Available at  / 17 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Volume

ISBN 9781605352909

Description

Teaching cell biology can be a daunting task because the field is so vast and rapidly moving, characterized by a continual explosion of new information. The challenge is how to teach students the fundamental concepts without becoming bogged down in details. Students need to understand the principles of cell biology and be able to appreciate new advances, rather than just memorizing "the facts" as we see them today. At the same time, the material must be presented in sufficient depth to thoughtfully engage students and provide a sound basis for further studies. The Cell, Seventh Edition, provides a balance of concepts and details that meets the needs of today's students and their teachers. Written by an active scientist and experienced educator, this textbook combines readability and cohesiveness with comprehensive and up-to-date science.

Table of Contents

Preface PART I. FUNDAMENTALS AND FOUNDATIONSChapter 1. An Overview of Cells and Cell ResearchChapter 2. Molecules and MembranesChapter 3. Bioenergetics and MetabolismChapter 4. Fundamentals of Molecular BiologyChapter 5. Genomics, Proteomics, and Systems BiologyPART II. THE FLOW OF GENETIC INFORMATIONChapter 6. Genes and GenomesChapter 7. Replication, Maintenance, and Rearrangements of Genomic DNAChapter 8. RNA Synthesis and ProcessingChapter 9. Protein Synthesis, Processing, and RegulationPART III. CELL STRUCTURE AND FUNCTIONChapter 10. The NucleusChapter 11. Protein Sorting and TransportChapter 12. Mitochondria, Chloroplasts, and PeroxisomesChapter 13. The Cytoskeleton and Cell MovementChapter 14. The Plasma MembraneChapter 15. Cell Walls, the Extracellular Matrix, and Cell InteractionsPART IV. CELL REGULATION Chapter 16. Cell SignalingChapter 17. The Cell CycleChapter 18. Cell Death and Cell RenewalChapter 19. CancerAnswers to QuestionsGlossaryIllustration CreditsIndex
Volume

: [International ed] ISBN 9781605355634

Description

The Cell, Seventh Edition provides a balance of concepts and details that meets the needs of today's students and their teachers. Written by an active scientist and experienced educator, this textbook combines readability and cohesiveness with comprehensive and up-to-date science. In keeping with prior editions, the new Seventh Edition: Is ideally suited in length and complexity for sophomore- and junior-level courses at the undergraduate level. Can be covered in a single semester. Students can master the material in its entirety, rather than sampling a small fraction from a much larger text. Is written in an efficient and compact style, covering a broad range of material in a direct and pedagogically approachable manner. Focuses on the molecular biology of cells as a unifying theme, with topics such as developmental biology, the nervous system, the immune system, and plant biology being discussed as examples of more general principles. Features 'Key Experiment' and 'Molecular Medicine' boxes that highlight the experimental nature of molecular and cellular biology and convey the excitement and medical relevance of research in this area.

Table of Contents

Part I. Fundamentals and Foundations.- 1. An Overview of Cells and Cell Research.- New discussion of super-resolution light microscopy.- New Key Experiment: HeLa cells.- 2. Molecules and Membranes.- Reorganized to include discussion of enzymes and catalysis.- 3. Bioenergetics and Metabolism.- Reorganized to include discussion of the mechanisms of oxidative phosphorylation and photosynthesis.- 4. Fundamentals of Molecular Biology.- Additional discussion of real-time PCR.- New discussion of the CRISPR/Cas system.- 5. Genomics, Proteomics, and Systems Biology.- New chapter focusing on genomics, proteomics, and systems biology.- Added discussion of next-generation sequencing.- New section on Synthetic Biology.- New Molecular Medicine: Malaria and Synthetic Biology.- Part II. The Flow of Genetic Information.- 6. Genes and Genomes.- Updated discussion of noncoding RNAs.- New Key Experiment: The ENCODE Project.- 7. Replication, Maintenance, and Rearrangements of Genomic DNA.- New discussion of DNA rearrangement and yeast mating types.- 8. RNA Synthesis and Processing.- Discussion of the role of ?-ketoglutarate in catabolite repression.- Updated information on insulators and transcriptional domains.- New section on Chromatin and Epigenetics.- Updated discussion of lncRNAs.- 9. Protein Synthesis, Processing, and Regulation.- New discussion of prions.- Updated information on protein modification by ubiquitin and SUMO.- New Molecular Medicine: Alzheimer's Disease.- Part III. Cell Structure and Function.- 10. The Nucleus.- New information on the organization of chromosome domains within the nucleus.- Updated discussion of nuclear bodies.- 11. Protein Sorting and Transport: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes.- Updated discussion of the insertion of membrane proteins in the ER.- New information on protein trafficking through the Golgi.- Updated discussion of vesicle docking and fusion.- 12. Mitochondria, Chloroplasts, and Peroxisomes.- Updated discussion of chloroplast genomes and protein import.- New information on peroxisome biogenesis.- New Molecular Medicine: Peroxisome Biogenesis Disorders.- 13. The Cytoskeleton and Cell Movement.- Updated discussion of actin filament remodeling at the leading edge.- 14. The Plasma Membrane.- Updated discussion of plasma membrane domains, lipid rafts and caveolae.- New information on clathrin-independent endocytosis.- Updated Molecular Medicine to include new information on drug treatment of cystic fibrosis.- 15. Cell Walls, the Extracellular Matrix, and Cell Interactions.- New discussion of the role of bacterial cytoskeletal proteins in cell wall synthesis and cell shape.- Updated information on a-catenin linkage to actin.- Part IV. Cell Regulation.- 16. Cell Signaling.- Chapter reorganized to focus on integrated signaling pathways.- 17. The Cell Cycle.- Expanded discussion of the initiation of DNA synthesis and role of APC/C.- New information on the spindle assembly checkpoint.- 18. Cell Death and Cell Renewal.- Expanded discussion of programmed cell death by autophagy and necroptosis.- New information on stem cell niches.- 19. Cancer.- Updated discussion of cancer genomics.- New information on targeted therapies.

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Details

  • NCID
    BB20711148
  • ISBN
    • 9781605352909
    • 9781605355634
  • LCCN
    2012051640
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Sunderland, Mass.
  • Pages/Volumes
    xxv, 832 p.
  • Size
    29 cm
  • Classification
  • Subject Headings
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