Viral nanotechnology

著者

    • Khudyakov, Yury
    • Pumpens, Paul

書誌事項

Viral nanotechnology

edited by Yury Khudyakov, Paul Pumpens

CRC Press, Taylor & Francis Group, c2016

  • : hard

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Viral Nanotechnology presents an up-to-date overview of the rapidly developing field of viral nanotechnology in the areas of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Its chapters are by leading researchers and practitioners, making it both a comprehensive and indispensable resource for study and research. The field of viral nanotechnology is new and quickly expanding due to increasing demand of the applications already developed. The editors identify viral nanotechnology as a significant science that concerns itself with how to use the molecular modules that the distinctly different science of molecular engineering only constructs. The current potential applications of viral technology are manifold, with opportunities to revolutionize practices in photonics, catalysis, electronics, energy, biomedicine, health care, and public health. This book emphasizes using viral nanotechnology to improve health. A special emphasis is placed upon using viral nanotechnology for developing vaccines. In addition, it documents viral nanotechnology's use as a powerful tool for developing drugs and genetic therapies. There is also great potential in its use as a means for diagnostics, including the development of diagnostic reagents and novel imaging technologies for detecting disease and infectious agents. Viral nanotechnology's rapid and exciting growth is due to the need for new tools in the prevention, diagnosis, and treatment of disease. The contributors to this volume approach each chapter with the hope that their research and practices will contribute to an improvement in health and life on an unprecedented scale in human history.

目次

Preface. Editors. Contributors. Introduction. Introduction to Capsid Architecture. Self-Assembling Virus-like and Virus-Unlike Particles. Electron Cryomicroscopy and Image Reconstruction of Viral Nanoparticles. X-Ray Analysis of Viral Nanoparticles. Computational Methods for Engineering Protein 3D Nanoobjects. Viral Nanoparticles: Principles of Construction and Characterization. Immunology of Virus-like Particles. Nanomedicine: General Considerations and Examples. Virus-like Particles: A Versatile Tool for Basic and Applied Research on Emerging and Reemerging Viruses. Virus-like Particles Derived from Hepatitis Viruses. History and Potential of Hepatitis B Virus Core as a VLP Vaccine Platform. SplitCore: Advanced Nanoparticulate Molecular Presentation Platform Based on the Hepatitis B Virus Capsid. Use of VLPs in the Design of Malaria Vaccines. Use of HBcAg as an Adjuvant in DNA-Based Vaccines: An Unexpected Journey. Bacteriophage Virus-like Particles as a Platform for Vaccine Discovery. Production of Virus-like Particles in Plants. Bionanomaterials from Plant Viruses. Assembly of Bluetongue Virus-like Particle: Multiprotein Complex and Its Use as Vaccine. Virus-like Particles Based on Polyomaviruses and Human Papillomaviruses as Vectors for Vaccines, Preventive and Therapeutic Immunotherapy, and Gene Delivery. Applications of Viral Nanoparticles Based on Polyomavirus and Papillomavirus Structures. Nanoparticles of Norovirus. Virus-like Particle Enzyme Encapsulation: Confined Catalysts and Metabolic Materials. Principles of Design of Virus Nanoparticles for Imaging Application. Enveloped Viruses with Single-Stranded Negative RNA Genome as Objects and Subjects of VLP Nanotechnology. Traditional and Novel Trends in Influenza Vaccines. Retrovirus-Derived Virus-like Particles. Cancer Therapy Applying Viral Nanoparticles. Alphaviral Vectors for Cancer Treatment. Synthetic Virus-like Particles in Vaccine Design. Index.

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