The IACUC handbook

Author(s)

• Silverman, Jerald
• Suckow, Mark A.
• Murthy, Sreekant

Bibliographic Information

The IACUC handbook

edited by Jerald Silverman, Mark A. Suckow, Sreekant Murthy

CRC Press, Taylor & Francis Group, c2014

3rd ed

• : hardcover

Note

Includes bibliographical references and index

Description and Table of Contents

Description

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution's IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee. This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare's Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.

Table of Contents

Introduction. Origins of the IACUC. Circumstances Requiring an IACUC. Creation of an IACUC. Reporting Lines of the IACUC. General Composition of the IACUC and Specific Roles of the IACUC Members. Frequency and Conduct of Regular IACUC Meetings. General Format of IACUC Protocol Forms. Submission and Maintenance of IACUC Protocols. General Concepts of Protocol Review. Amending IACUC Protocols. Continuing Review of Protocols. Justification for the Use of Animals. Justification of the Number of Animals to Be Used. Animal Acquisition and Disposition. Animal Housing, Use Sites, and Transportation. Pain and Distress. Euthanasia. Surgery. Antigens, Antibodies, and Blood Collection. Occupational Health and Safety. Personnel Training. Confidential and Proprietary Information. General Concepts of the Program Review and Facility Inspection. Inspection of Animal Housing Areas. Inspection of Individual Laboratories. Inspection of Surgery Areas. Assessment of Veterinary Care. Laboratory Animal Enrichment. Animal Mistreatment and Protocol Noncompliance. Postapproval Monitoring. The European Ethical Review Framework: Collaborative Issues. Index.

by "Nielsen BookData"

• NCID: BB21681905
• ISBN:
  • 9781466555648
• LCCN: 2013049106
• Country Code: us
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Boca Raton, Fla.
• Pages/Volumes: 807 p.
• Size: 27 cm
• Classification:
  • LCC : HV4708
  • NLM : QY 54
  • DC23 : 179/.3
• Subject Headings:
  • MESH : National Institutes of Health (U.S.). Institutional Animal Care and Use Committee
  • MESH : Animal Care Committees -- organization & administration
  • MESH : Animal Welfare
  • MESH : Animal Experimentation -- legislation & jurisprudence
  • MESH : Animals, Laboratory