Video bioinformatics : from live imaging to knowledge
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Bibliographic Information
Video bioinformatics : from live imaging to knowledge
(Computational biology, 22)
Springer, c2015
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Includes bibliographical references and index
Description and Table of Contents
Description
The advances of live cell video imaging and high-throughput technologies for functional and chemical genomics provide unprecedented opportunities to understand how biological processes work in subcellularand multicellular systems. The interdisciplinary research field of Video Bioinformatics is defined by BirBhanu as the automated processing, analysis, understanding, data mining, visualization, query-basedretrieval/storage of biological spatiotemporal events/data and knowledge extracted from dynamic imagesand microscopic videos. Video bioinformatics attempts to provide a deeper understanding of continuousand dynamic life processes.Genome sequences alone lack spatial and temporal information, and video imaging of specific moleculesand their spatiotemporal interactions, using a range of imaging methods, are essential to understandhow genomes create cells, how cells constitute organisms, and how errant cells cause disease. The bookexamines interdisciplinary research issues and challenges with examples that deal with organismal dynamics,intercellular and tissue dynamics, intracellular dynamics, protein movement, cell signaling and softwareand databases for video bioinformatics.Topics and Features* Covers a set of biological problems, their significance, live-imaging experiments, theory andcomputational methods, quantifiable experimental results and discussion of results.* Provides automated methods for analyzing mild traumatic brain injury over time, identifying injurydynamics after neonatal hypoxia-ischemia and visualizing cortical tissue changes during seizureactivity as examples of organismal dynamics* Describes techniques for quantifying the dynamics of human embryonic stem cells with examplesof cell detection/segmentation, spreading and other dynamic behaviors which are important forcharacterizing stem cell health* Examines and quantifies dynamic processes in plant and fungal systems such as cell trafficking,growth of pollen tubes in model systems such as Neurospora Crassa and Arabidopsis* Discusses the dynamics of intracellular molecules for DNA repair and the regulation of cofilintransport using video analysis* Discusses software, system and database aspects of video bioinformatics by providing examples of5D cell tracking by FARSIGHT open source toolkit, a survey on available databases and software,biological processes for non-verbal communications and identification and retrieval of moth imagesThis unique text will be of great interest to researchers and graduate students of Electrical Engineering,Computer Science, Bioengineering, Cell Biology, Toxicology, Genetics, Genomics, Bioinformatics, ComputerVision and Pattern Recognition, Medical Image Analysis, and Cell Molecular and Developmental Biology.The large number of example applications will also appeal to application scientists and engineers.Dr. Bir Bhanu is Distinguished Professor of Electrical & C omputer Engineering, Interim Chair of theDepartment of Bioengineering, Cooperative Professor of Computer Science & Engineering, and MechanicalEngineering and the Director of the Center for Research in Intelligent Systems, at the University of California,Riverside, California, USA.Dr. Prue Talbot is Professor of Cell Biology & Neuroscience and Director of the Stem Cell Center and Core atthe University of California Riverside, California, USA.
Table of Contents
Part I: Video Bioinformatics: An Introduction
Live Imaging and Video Bioinformatics
Bir Bhanu and Prue Talbot
Video Bioinformatics Methods for Analyzing Cell Dynamics: A Survey
Nirmalya Ghosh
Part II: Organismal Dynamics: Analyzing Brain Injury and Disease
High and Low Level Contextual Modeling for the Detection of Mild-Traumatic Brain Injury
Anthony Bianchi, Bir Bhanu and Andre Obenaus
Automated Identification of Injury Dynamics after Neonatal Hypoxia-Ischemia
Nirmalya Ghosh, Stephen Ashwal and Andre Obenaus
A Real-Time Analysis of Traumatic Brain Injury from T2 Weighted Magnetic Resonance Images using a Symmetry-Based Algorithm
Ehsan T. Esfahani, Devin W. McBride, Somayeh B. Shafiei and Andre Obenaus
Visualizing Cortical Tissue Optical Changes during Seizure Activity with Optical Coherence Tomography
Melissa M. Eberle, Carissa L. Rodriguez, Jenny I. Szu, Yan Wang, Mike S. Hsu, Devin K. Binder and B. Hyle Park
Part III: Dynamics of Stem Cells
Bio-Inspired Segmentation and Detection Methods for Human Embryonic Stem Cells
Benjamin X. Guan, Bir Bhanu, Prue Talbot and Jo-Hao Weng
A Video Bioinformatics Method to Quantify Cell Spreading and Its Application to Cells Treated with Rho-associated Protein Kinase and Blebbistatin
Jo-Hao Weng, Rattapol Phandthong and Prue Talbot
Evaluation of Dynamic Cell Processes an
d Behavior Using Video Bioinformatics Tools
Sabrina C. Lin, Henry Yip, Rattapol Phandthong, Barbara Davis and Prue Talbot
Part IV: Dynamic Processes in Plant and Fungal Systems
Video Bioinformatics: A New Dimension in Quantifying Plant Cell Dynamics
Nolan Ung and Natasha V Raikhel
Understanding Growth of Pollen Tube in Video
Asongu L. Tambo, Bir Bhanu, Nan Luo and Zhenbiao Yang
Automatic Image Analysis Pipeline for Studying Growth in Katya Mkrtchyan, Anirban Chakraborty, Min Liu and Amit Roy-Chowdhury
Quantitative Analyses using Video Bioinformatics and Image Analysis Tools During Growth and Development in the Multicellular Fungus Neurospora Crassa
Ilva E. Cabrera, Asongu L. Tambo, Alberto C. Cruz, Benjamin X. Guan, Bir Bhanu and Katherine A. Borkovich
Part V: Dynamics of Intracellular Molecules
Quantification of the Dynamics of DNA Repair to Ionizing Radiation via Colocalization of 53BP1 and H2AX
Torsten Groesser, Gerald Fontenay, Ju Han, Hang Chang and Bahram Parvin
A Method to Regulate Cofilin Transport Using Optogenetics and Live Video Analysis
Atena Zahedi, Vincent On and Irnya Ethell
Part VI: Software, Systems and Databases
Integrated 5-D Cell Tracking and Linked Analytics in the FARSIGHT Open Source Toolkit
Amine Merouane, Arunchalam Narayanaswamy and Badrinath Roysam
Video Bioinfo
rmatics Databases and Software
Ninad S. Thakoor, Alberto C. Cruz and Bir Bhanu
Understanding of the Biological Process of Non-Verbal Communication: Facial Emotion and Expression Recognition
Alberto C. Cruz, Bir Bhanu and Ninad S. Thakoor
Identification and Retrieval of Moth Images Based on Wing Patterns
Linan Feng, Bir Bhanu and John Heraty
by "Nielsen BookData"