The physiological basis of metabolic bone disease

著者

書誌事項

The physiological basis of metabolic bone disease

edited by Howard A. Morris, Paul H. Anderson, B. E. Christopher Nordin

CRC Press, 2014

大学図書館所蔵 件 / 全1件

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注記

Includes bibliographical references and index

Summary: "Physiology and medicine are interrelated disciplines, and this is perhaps nowhere more apparent than in the field of mineral metabolism. This book presents information on the physiological principles regulating the response of mineral homeostasis on genetic, molecular, environmental, and nutritional factors. Chapters cover calcium and vitamin D nutrition, intestinal calcium absorption, plasma calcium homeostasis, renal handling of calcium, calcium sensing receptors, plasma phosphate homeostasis, endocrine actions of vitamin D, parathyroid hormone, calcitonin, and the calcification process"--Provided by publisher

収録内容

  • Nutritional requirements for calcium and vitamin D
  • Physiology of vitamin D, calcium, and phosphate absorption
  • Plasma and extracellular fluid calcium homeostasis in relation to metabolic bone disease: the role of the kidney
  • Calcium-sensing receptor: coordination of mineral metabolism and therapeutic target for metabolic bone disorders
  • Parathyroid hormone : its role in calcium and phosphate homeostasis
  • Phosphate homeostasis and metabolic bone disease
  • Vitamin D.: activities for bone health
  • Physiological actions of calcitonin
  • Definition, diagnosis and significance of osteoporosis

内容説明・目次

内容説明

Research into metabolic bone disease has made remarkable progress over the last 20 years, with the identification of numerous new molecules and pathways regulating bone cells as well as their plasma milieu. Their activities are largely regulated by the physiological status of the body incorporating the biochemical, physical and mechanical functions of bone, kidney and intestinal tissues. The Physiological Basis of Metabolic Bone Disease integrates the knowledge derived from molecular techniques with the fundamental principles of the physiology of these organs. The book places particular emphasis on bone cell activities and the regulation of plasma calcium, phosphate homeostasis, and whole body nutrition. It reviews the nutritional requirements for calcium and vitamin D for the prevention of osteoporosis. It covers vitamin D, calcium and phosphate absorption; calcium sensing receptors; the role of parathyroid hormone; physiological actions of calcitonin; and the diagnosis and significance of osteoporosis. Reviewing the physiological significance of advances in the molecular biology of metabolic bone disease, this book provides a valuable reference for researchers as well as practicing clinicians.

目次

Nutritional Requirements for Calcium and Vitamin D. Physiology of Vitamin D, Calcium, and Phosphate Absorption. Plasma and Extracellular Fluid Calcium Homeostasis in Relation to Metabolic Bone Disease: Role of Kidneys. Calcium Sensing Receptors: Coordinators of Mineral Metabolism and Therapeutic Targets for Metabolic Bone Disorders. Parathyroid Hormone: Its Role in Calcium and Phosphate Homeostasis. Phosphate Homeostasis and Metabolic Bone Disease. Vitamin D: Activities for Bone Health. Physiological Actions of Calcitonin. Definition, Diagnosis, and Significance of Osteoporosis. Index.

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