Epigenetics and neuroendocrinology : clinical focus on psychiatry
著者
書誌事項
Epigenetics and neuroendocrinology : clinical focus on psychiatry
（Epigenetics and human health / series editors, Robert Feil, Mario Noyer-Weidner, Jörn Walter）
Springer, c2016
- v. 1
- v. 2
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注記
Includes bibliographical references
内容説明・目次
- 巻冊次
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v. 1 ISBN 9783319244914
内容説明
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.
目次
- Foreword by Dietmar Spengler & Elisabeth Binder.- Part I, Epigenetics And The Stress System.- I.1 From vulnerability to neurotoxicity: A developmental approach to the effects of stress on brain and behavior .- I.2 Dynamic regulation of chromatin modification and transcription by GR and the steroid receptors .- I.3 NR receptor coactivators.- I.4 Glucocorticoid-dependent epigenetic regulation of Fkbp5.- I.5 Epigenetic programming of the HPA axis by early-life adversity.- I.6 Epigenetic programming of hypothalamic Pomc regulates feeding and obesity.- I.7 Effects of maternal care in monkeys.- I.8 Stress, transposons and the brain epigenome.- Part II
- Epigenetics And Sexual Differentiation.- II.1 Neuroepigenetics of sexual differentiation of brain and behavior.- II.2 Differential regulation of androgen receptor and DNA methylation in songbirds.- II.3 chapter title "GnRH gene/Kiss gene, sexual dimorphism, puberty.
- 巻冊次
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v. 2 ISBN 9783319299006
内容説明
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.
目次
- PART III
- EPIALLELES AND NEUROENDOCRINOLOGY .- III.1 Fkbp5 epiallels.- III.2 Genomic regulation of the PACAP receptor, PAC1, and implications for psychiatric disease.- III.3 Prodynorphin epialleles.- PART IV
- TRANSGENERATIONAL REGULATION OF THE NEUROENDOCRINE SYSTEM.- IV.1 Epigenetic Risk Factors for Diseases: A Transgenerational Perspective.- IV.2 Epigenetic alteration to NR3C1 and HSD11B2 and the developmental origins of mental disease risk.- IV.3 Intergenerational effects of PTSD on offspring glucocorticoid receptor methylation.- PART V
- EPIGENETIC BIOMARKERS AND NEUROENDOCRINOLOGY.- V.1 Epigenetic biomarkers for early life adversity.- V.2 Epigenetic biomarkers of maternal stress.- V.3 Epigenetic modifications in borderline personality disorder.- V.4 Oxytocin receptors and neurobehavior.- V.5 Psychosocial stress and DNA methylation.
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