Bioprocess engineering : basic concepts

Author(s)

    • Shuler, Michael L.
    • Kargı, Fikret
    • DeLisa, Matthew

Bibliographic Information

Bioprocess engineering : basic concepts

Michael L.Shuler, Fikret Kargi, Matthew De Lisa

(Prentice-Hall international series in the physical and chemical engineering sciences)

Prentice Hall, c2017

3rd ed

Available at  / 3 libraries

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Note

Previous edition: Englewood Cliffs: Prentice Hall, 2000

Description and Table of Contents

Description

The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world's leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses.

Table of Contents

Part I: The Basics of Biology: An Engineer's Perspective Chapter 1: What Is a Bioprocess Engineer? Chapter 2: An Overview of Biological Basics Chapter 3: Enzymes Chapter 4: How Cells Work Chapter 5: Major Metabolic Pathways Chapter 6: How Cells Grow Chapter 7: Stoichiometry of Microbial Growth and Product Formation Chapter 8: How Cellular Information Is Altered Part II: Engineering Principles for Bioprocesses Chapter 9: Operating Considerations for Bioreactors for Suspension and Immobilized Cultures Chapter 10: Selection, Scale-Up, Operation, and Control of Bioreactors Chapter 11: Recovery and Purification of Products Chapter 12: Bioprocess Considerations in Using Animal Cell Cultures Chapter 13: Bioprocess Considerations in Using Plant Cell Cultures Chapter 14: Utilizing Genetically Engineered Organisms Chapter 15: Medical Applications of Bioprocess Engineering Chapter 16: Multiple Species in Culture Appendix A: Traditional Industrial Bioprocesses

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Details

  • NCID
    BB23456218
  • ISBN
    • 9780137062706
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Boston
  • Pages/Volumes
    xxi, 632 p.
  • Size
    24 cm
  • Classification
  • Subject Headings
  • Parent Bibliography ID
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