An insider's guide to clinical trials

書誌事項

An insider's guide to clinical trials

Curtis L. Meinert

Oxford University Press, c2011

  • : pbk. : alk. paper

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注記

Includes bibliographical references (p. [247]-259) and indexes

内容説明・目次

内容説明

Clinical trials receive a lot of media attention; we hear or read about them almost daily in reports heralding new and promising treatments or reports raising questions about the safety or efficacy of an established treatment. The randomized trial is the foundation of evidence-based medicine and the cornerstone for comparative effectiveness research. This book is designed for budding students of clinical trials, novice researchers, and for the serious lay reader wanting to know more about the inner workings of trials, how they are reported, who and what gets studied, what to make of results, and how to shop for trials as a patient. Written with wit and charm, this guide will interest readers in way that formal, didactic texts cannot.

目次

Contents Preface Chapter 1: Introduction Chapter 2: The language of clinical trials Chapter 3: The recipe for trials Chapter 4: The stages of trials Chapter 5: The anatomy of trials Chapter 6: Authorship and credits Chapter 7: The nature of trials Chapter 8: The ethics of trials Chapter 9: Regulation of trials Chapter 10: Research misconduct Chapter 11: Myths regarding trials Chapter 12: "Tricks" of the trade from a cynic Chapter 13: Reading between the lines, or how to read a journal article Chapter 14: Critics and criticisms Chapter 15: What to make of results Chapter 16: Biostatistics 101 Chapter 17: Subgroup analysis vs data dredging Chapter 18: Meta-analysis and systematic reviews Chapter 19: Re-Search Chapter 20: Shopping for a trial? Chapter 21: Readings Chapter 22: Clinical trials and our health Chapter 23: Final exam Chapter 24: Last words Appendix - The Mother Test for Designers of Trials - Rating Index for Clinical Trials - A Patient's Guide for Deciding Whether to Enroll in a Randomized Trial - Abbreviations References Index

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