NF-κB-related genetic diseases
著者
書誌事項
NF-κB-related genetic diseases
（SpringerBriefs in biochemistry and molecular biology）
Springer, c2016
- : pbk
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注記
Other authors: Alessandra Pescatore, Jérémie Gautheron, Francesca Fusco, Matilde Valeria Ursini, Anna Senegas
Includes bibliographical references
内容説明・目次
内容説明
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
目次
1) The NF-kB signaling pathways: players and Functions.- 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation.- 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation.- 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling.- 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.
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