NF-κB-related genetic diseases

著者
    • Courtois, Gilles
    • Pescatore, Alessandra
    • Gautheron, Jérémie
    • Fusco, Francesca
    • Ursini, Matilde Valeria
    • Senegas, Anna
書誌事項

NF-κB-related genetic diseases

Gilles Courtois ... [et al.]

(SpringerBriefs in biochemistry and molecular biology)

Springer, c2016

  • : pbk

この図書・雑誌をさがす
注記

Other authors: Alessandra Pescatore, Jérémie Gautheron, Francesca Fusco, Matilde Valeria Ursini, Anna Senegas

Includes bibliographical references

内容説明・目次

内容説明

This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.

目次

1) The NF-kB signaling pathways: players and Functions.- 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation.- 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation.- 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling.- 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.

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