Molybdenum and tungsten enzymes

著者

    • Hille, Russ
    • Schulzke, Carola
    • Kirk, Martin L.

書誌事項

Molybdenum and tungsten enzymes

edited by Russ Hille, Carola Schulzke, and Martin L. Kirk

(RSC metallobiology series / editor in chief, David Garner, 5-7)

Royal Society of Chemistry, c2017

  • : Biochemistry
  • : Bioinorganic chemistry
  • : Spectroscopic and theorethical investigations

タイトル別名

Molybdenum and tungsten enzymes : Biochemistry

Molybdenum and tungsten enzymes : Bioinorganic chemistry

Molybdenum and tungsten enzymes : Spectroscopic and theorethical investigations

大学図書館所蔵 件 / 3

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

巻冊次

: Biochemistry ISBN 9781782620891

内容説明

There has been enormous progress in our understanding of molybdenum and tungsten enzymes and relevant inorganic complexes of molybdenum and tungsten over the past twenty years. This set of three books provides a timely and comprehensive overview of the field and documents the latest research. The first volume in the set focusses on the enzymes themselves, and discusses active sites and substrate channels of relevant proteins. The book begins with an introductory overview of the whole field. Chapters are contributed by world leaders and topics covered include pyranopterin cofactor biosynthesis and incorporation of the mature cofactor into apoprotein. Subsequent volumes cover the bioinorganic chemistry relevant to these enzymes and the full range of spectroscopic and theoretical methods that are used to investigate their physical and electronic structure and function. This text will be a valuable reference to workers both inside and outside the field, including graduate students and young investigators interested in developing new research programs in this area.

目次

  • Part I Molybdenum- and tungsten-containing enzymes
  • Abundance, ubiquity, and evolution of molybdoenzymes
  • Molybdenum cofactor biosynthesis
  • Bacterial molybdoenzymes
  • The prokaryotic Mo/W-bisPGD enzyme family
  • Enzymes of the xanthine oxidase family
  • The sulfite oxidase family of Mo enzymes
  • Nitrogenase
  • Tungsten-containing enzymes
  • Part II Introduction and overview of synthetic Mo and W chemistry
  • Synthesis of mono- and bisdithiolene Mo and W model compounds
  • Pterin‐inspired Model Compounds of Molybdenum Enzymes
  • Synthesis of models for the xanthine oxidase family of enzymes
  • Electron transfer mechanisms in Mo and W compounds
  • Comparative kinetics of enzymes and models
  • Models of the metal clusters of nitrogenase
  • Part III Overview of spectroscopic and electronic studies of Mo and W enzymes
  • Spectroscopic and electronic structure studies of Mo model compounds and enzymes
  • Electron paramagnetic resonance studies of molybdenum enzymes
  • X-ray absorption spectroscopic studies of molybdenum enzymes
  • Electrochemistry of molybdenum and tungsten enzymes
  • Computational studies of molybdenum and tungsten enzymes
  • Nitrogen Fixation in Nitrogenase and Related Small-Molecule Models
巻冊次

: Bioinorganic chemistry ISBN 9781782628774

内容説明

There has been enormous progress in our understanding of molybdenum and tungsten enzymes and relevant inorganic complexes of molybdenum and tungsten over the past twenty years. This set of three books provides a timely and comprehensive overview of the field and documents the latest research. Building on the first volume that focussed on biochemistry aspects, the second volume in the set focusses on the inorganic complexes that model the structures and reactivity of the active sites of each major group of molybdenum and tungsten enzymes. Special attention is given to synthetic strategies, reaction mechanism and chemical kinetics of these systems. The introductory chapter provides a useful overview and places the topic of the book into a wider context. This text will be a valuable reference to workers both inside and outside the field, including graduate students and young investigators interested in developing new research programs in this area.

目次

  • Part I Molybdenum- and tungsten-containing enzymes
  • Abundance, ubiquity, and evolution of molybdoenzymes
  • Molybdenum cofactor biosynthesis
  • Bacterial molybdoenzymes
  • The prokaryotic Mo/W-bisPGD enzyme family
  • Enzymes of the xanthine oxidase family
  • The sulfite oxidase family of Mo enzymes
  • Nitrogenase
  • Tungsten-containing enzymes
  • Part II Introduction and overview of synthetic Mo and W chemistry
  • Synthesis of mono- and bisdithiolene Mo and W model compounds
  • Pterin‐inspired Model Compounds of Molybdenum Enzymes
  • Synthesis of models for the xanthine oxidase family of enzymes
  • Electron transfer mechanisms in Mo and W compounds
  • Comparative kinetics of enzymes and models
  • Models of the metal clusters of nitrogenase
  • Part III Overview of spectroscopic and electronic studies of Mo and W enzymes
  • Spectroscopic and electronic structure studies of Mo model compounds and enzymes
  • Electron paramagnetic resonance studies of molybdenum enzymes
  • X-ray absorption spectroscopic studies of molybdenum enzymes
  • Electrochemistry of molybdenum and tungsten enzymes
  • Computational studies of molybdenum and tungsten enzymes
  • Nitrogen Fixation in Nitrogenase and Related Small-Molecule Models
巻冊次

: Spectroscopic and theorethical investigations ISBN 9781782628781

内容説明

There has been enormous progress in our understanding of molybdenum and tungsten enzymes and relevant inorganic complexes of molybdenum and tungsten over the past twenty years. This set of three books provides a timely and comprehensive overview of the field and documents the latest research. Building on the first and second volumes that focussed on biochemistry and bioinorganic chemistry aspects, the third volume focusses on spectroscopic and computational methods that have been applied to both enzymes and model compounds. A particular emphasis is placed on how these important studies have been used to reveal critical components of enzyme mechanisms. This text will be a valuable reference to workers both inside and outside the field, including graduate students and young investigators interested in developing new research programs in this area.

目次

  • Part I Molybdenum- and tungsten-containing enzymes
  • Abundance, ubiquity, and evolution of molybdoenzymes
  • Molybdenum cofactor biosynthesis
  • Bacterial molybdoenzymes
  • The prokaryotic Mo/W-bisPGD enzyme family
  • Enzymes of the xanthine oxidase family
  • The sulfite oxidase family of Mo enzymes
  • Nitrogenase
  • Tungsten-containing enzymes
  • Part II Introduction and overview of synthetic Mo and W chemistry
  • Synthesis of mono- and bisdithiolene Mo and W model compounds
  • Pterin‐inspired Model Compounds of Molybdenum Enzymes
  • Synthesis of models for the xanthine oxidase family of enzymes
  • Electron transfer mechanisms in Mo and W compounds
  • Comparative kinetics of enzymes and models
  • Models of the metal clusters of nitrogenase
  • Part III Overview of spectroscopic and electronic studies of Mo and W enzymes
  • Spectroscopic and electronic structure studies of Mo model compounds and enzymes
  • Electron paramagnetic resonance studies of molybdenum enzymes
  • X-ray absorption spectroscopy of molybdenum and tungsten Enzymes
  • Electrochemistry of molybdenum and tungsten enzymes
  • Computational studies of molybdenum and tungsten enzymes
  • Nitrogen Fixation in Nitrogenase and Related Small-Molecule Models

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