Rodent models of stroke
著者
書誌事項
Rodent models of stroke
（Neuromethods, 120）（Springer protocols）
Humana Press, c2016
2nd ed
- : hbk
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注記
Previous edition: 2010
内容説明・目次
内容説明
This second edition provides updated and expanded chapters that critically address the issues or rodent stroke modeling, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. Rodent Models of Stroke, Second Edition aims to help its readers understand the limitations and the opportunities of modeling stroke in rodents and enable them to conduct experiments which will not only improve our understanding of the pathophysiology of this devastating disorder but also serve as the basis for developing new highly effective treatments. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Authoritative and practical, Rodent Models of Stroke, Second Edition provides authoritative reviews of the most commonly used, well-honed approaches in the field today.
目次
1. From Bedside to Bench: How Clinical Reality Should Instruct Stroke Modeling
Dirk M. Hermann and Thorsten R. Doeppner
2. How to Avoid Bumping into the Translational Roadblock
Malcolm Macleod and Emily Sena
3. Modeling Focal Cerebral Ischemia in Rodents: Introduction and Overview Vincent Prinz and Matthias Endres
4. Focal Cerebral Ischemia in the Mouse and Rat by Intraluminal Suture
Ludmila Belayev, Matthias Endres, and Vincent Prinz
5. Focal Ischemia Models: Middle Cerebral Artery Occlusion Induced by Electrocoagulation, Occluding devices and Endothelin-1
I Mhairi Macrae
6. Mouse Model of in situ Thromboembolic Stroke and Reperfusion
Orset Cyrille, Le Behot Audrey, Bonnet Anne-Laure, Maysami Samaneh, and Vivien Denis
7. Photochemical Models of Focal Brain Ischemia
Anja Urbach and Otto W. Witte
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8. Housing in an Enriched Environment - A Tool to Study Functional Recovery after Experimental Stroke
Karsten Ruscher and Tadeusz Wieloch
9. Modeling Risk Factors and Confounding Effects in Stroke
Barry McColl, David Howells, Nancy Rothwell, and Adam Denes
10. Effect of Anesthesia in Stroke Models
Richard J. Traystman<
11. Non-invasive Brain Imaging in Small Animal Stroke Models: MRI, PET and SPECT
Abraham Martin, Pedro Ramos-Cabrer, and Anna M. Planas
12. Non-invasive Optical Imaging in Rodent Models of Stroke Markus Vaas and Jan Klohs
13. Behavioral Testing in Rodent Models of Stroke, Part I
Rene Bernard, Mustafa Balkaya, and Andre Rex
14. Behavioral Testing in Rodent Models of Stroke -Part II
Gerlinde A.S. Metz
15. Combining Classical Comprehensive With Ethological Based, High Throughput Automated Behavioral Phenotyping for Rodent Models of Stroke
Anne-Christine Plank, Stephan von Hoersten, and Fabio Canneva
16. Histology and Infarct Volume Determination in Rodent Models of Stroke
Clemens Sommer
17. Ethics of Modeling of Cerebral Ischemia in Small Animals
Ute Lindauer
18. Quality Control and Standard Operating Procedures
Ulrich Dirnagl
19. Statistics in Experimental Stroke Research: From Sample Size Calculation to Data Description and Significance Testing
Ulrich Dirnagl
20. Complexities, Confounders, and Challenges in Experimental Stroke Research: A Checklist for Researchers and Reviewers Ulrich Dirnagl
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