Computational methods for processing and analysis of biological pathways
著者
書誌事項
Computational methods for processing and analysis of biological pathways
（SpringerBriefs in computer science）
Springer, c2017
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内容説明・目次
内容説明
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.
目次
Introduction
Networks and Pathways in Systems Pharmacology
Time Varying Methods for Pathway and Sub-Pathway Analysis
Identification of Differentially Expressed Pathways and Sub-Pathways
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