Control of biofilm infections by signal manipulation

著者
    • Balaban, Naomi
書誌事項

Control of biofilm infections by signal manipulation

Naomi Balaban, editor ; foreword by J. William Costerton

(Springer series on biofilms, v. 2)

Springer, c2008

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined. Thus, this is a hugely important work that describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors such as quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.

目次

Bacterial Cell-to-cell Communication (Quorum Sensing).- Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors.- Quorum-Sensing Inhibitory Compounds.- Mathematical Modeling of Quorum-Sensing Control in Biofilms.- Animal Models Commonly Used to Study Quorum-Sensing Inhibitors.- In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs.- Quorum Sensing in Streptococci.- Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation.- Clinical Wound Healing Using Signal Inhibitors.

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