Biosensors for medical applications
著者
書誌事項
Biosensors for medical applications
（Woodhead Publishing series in biomaterials, no. 45）
Woodhead Publishing, 2012
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson's disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications.Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications.With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors.
目次
Contributor contact details
Woodhead Publishing Series in Biomaterials
Introduction to biosensors
Part I: Principles and transduction approaches
Chapter 1: Electrochemical biosensors for medical applications
Abstract:
1.1 Introduction to electrochemical sensors
1.2 Electrochemical biosensing applications
1.3 Label-free approaches to electrochemical sensors
1.4 Conclusion and future trends
Chapter 2: Piezoelectric biosensors for medical applications
Abstract:
2.1 Introduction
2.2 Piezoelectric immunosensors
2.3 Piezoelectric genosensors
2.4 Piezoelectric biosensors with bio-mimetic receptors
2.5 Conclusions and future trends
Chapter 3: Nano-sized biosensors for medical applications
Abstract:
3.1 Introduction
3.2 Sensing modalities
3.3 Nanomaterial properties
3.4 Biosensors on the nanoscale
3.5 Conclusions
Chapter 4: Impedance interrogated affinity biosensors for medical applications: novel targets and mechanistic studies
Abstract:
4.1 Small molecule binding
4.2 Supramolecular structures
4.3 Electrochemical biosensor for clinical diagnostics
4.4 Challenges of carbohydrate sensing
4.5 Bioreceptors for carbohydrate sensing
4.6 Enzymes that act on carbohydrates
4.7 Impedimetric glucose biosensors
4.8 Impedimetric bacterial and viral immunosensors
4.9 Impedance and pathogens
4.10 Bioreceptors used in impedimetric pathogenic biosensor construction
4.11 Detection of exposure to infection
4.12 Conclusion
Chapter 5: Practical applications and protocols for enzyme biosensors
Abstract:
5.1 Introduction
5.2 Methods and approaches for using biosensors
5.3 Protocols for enzyme biosensors
Method
5.4 Problems arising from the construction and use of biosensors
Part II: Applications of medical biosensors
Chapter 6: Biosensors for DNA and RNA detection and characterization
Abstract:
6.1 Introduction to nucleic acids and base pairing
6.2 Principles of DNA/RNA sensing
6.3 Electrochemical DNA sensing
6.4 Optical DNA sensing
6.5 Quartz crystal microbalance and surface acoustic wave sensors
6.6 Microcantilever oligonucleotide sensors
6.7 Conclusions
Chapter 7: Biosensors for disease biomarker detection
Abstract:
7.1 Introduction
7.2 Disease biomarkers
7.3 Established technologies for disease biomarker detection
7.4 Proteins at surfaces
7.5 Emerging technologies for disease biomarker detection
7.6 Future trends
7.7 Sources of further information and advice
Chapter 8: Affibodies as an alternative to antibodies in biosensors for cancer markers
Abstract:
8.1 Introduction: cancer
8.2 Breast cancer
8.3 Human epidermal growth factor receptor 2 (HER2)
8.4 The immunoassay
8.5 Biosensors
8.6 Problems with antibodies
8.7 Affibodies
Chapter 9: Biosensors for drug testing and discovery
Abstract:
9.1 Introduction
9.2 Types of biosensor
9.3 Conclusion
9.4 Acknowledgements
Chapter 10: Biosensors for non-invasive measurements
Abstract:
10.1 Introduction
10.2 Biosensors for the detection of alcohol and lactate
10.3 Detection using electrochemical and amperometric biosensors
10.4 Detection using optical biosensors
10.5 Conclusions
Chapter 11: Wearable biosensors for medical applications
Abstract:
11.1 Introduction
11.2 Background
11.3 Considerations and requirements for wearable sensors
11.4 Types of wearable sensors
11.5 Temperature sensors
11.6 Mechanical sensors
11.7 Electrical sensors
11.8 Biological and chemical sensing
11.9 Clinical applications
11.10 Future trends
11.11 Sources of further information and advice
Index
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