Bioinformatics and the cell : modern computational approaches in genomics, proteomics and transcriptomics

著者
    • Xia, Xuhua
書誌事項

Bioinformatics and the cell : modern computational approaches in genomics, proteomics and transcriptomics

Xuhua Xia

Springer, c2018

2nd ed.

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注記

Includes bibliographical references (p. 443-484) and index

内容説明・目次

内容説明

This second edition integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular, cellular and evolutionary biology. This broad, unified approach is made possible, in large part, by the very wide scope of Dr. Xia's own research experience. The integration of genomics, proteomics and transcriptomics into a single volume makes this book required reading for anyone entering the new and emerging fields of Systems Biology and Evolutionary Bioinformatics.

目次

Blast and Fasta.- Sequence alignment.- Contig assembly.- DNA replication and viral evolution.- Gene and motif prediction.- Hidden Markov Models.- Gibbs Sampler.- Bioinformatics and vertebrate mitochondria.- Characterizing translation efficiency.- Protein isoelectric point.- Bioinformatics and Two-Dimensional Protein Separation.- Self-Organizing Map and other clustering Algorithms.- Molecular Phylogenetics.- Fundamentals of Proteomics.

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