Prostate cancer : methods and protocols
Author(s)
Bibliographic Information
Prostate cancer : methods and protocols
（Methods in molecular biology / John M. Walker, series editor, 1786）（Springer protocols）
Humana Press, c2018
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
This volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.
Table of Contents
1. Generation of Prostate Cancer Patient-derived Xenografts to Investigate Mechanisms of Novel Treatments and Treatment Resistance
Hung-Ming Lam, Holly M Nguyen, and Eva Corey
2. Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer
Ana-Rita Pedrosa, Alexandre Trindade, and Antonio Duarte
3. Methodologies Applied to Establish Cell Cultures in Prostate Cancer
Anne T Collins
4. Protocols for Migration and Invasion Studies in Prostate Cancer
Arjanneke F. van de Merbel, Geertje van der Horst, Jeroen T. Buijs, and Gabri van der Pluijm
5. Transplantable Animal Studies and Whole-body Optical Imaging in Prostate Carcinoma Geertje van der Horst, Maaike van der Mark, Henry Cheung, and Gabri van der Pluijm
6. Protocols for Tissue Microarrays in Prostate Cancer Studies
Tatjana Vlajnic, Serenella Eppenberger-Castori, and Lukas Bubendorf
7. Functional Studies on Steroid Receptors
Simon Schlanger and Hannelore V. Heemers
8. Protocols for Studies on TMPRSS/ERG in Prostate Cancer
Hubert Pakula, Douglas E. Linn, Daniel R. Schmidt, Marit Van Gorsel, Matthew G. Vander Heiden, and Zhe Li
9. Protocols for the Study of Taxanes Chemosensitivity in Prostate Cancer
M. Luz Flores and Carmen Saez
10. A Method for Prostate and Breast Cancer Cell Spheroid Cultures using Gelatin Methacryloyl-based Hydrogels
Christoph Meinert, Christina Theodoropoulos, Travis J Klein, Dietmar W Hutmacher, and Daniela Loessner
11. Protocols for Studies on Genetically Engineered Mouse Models in Prostate Cancer
Chris W.D. Armstrong, Oksana Lyubomska, Melissa J. LaBonte, and David J.J. Waugh
12. Protocols for Studies on Stromal Cells in Prostate Cancer
Damien A. Leach and Grant Buchanan
13. Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA
Manqi Zhang, William C Krause, and Irina U Agoulnik
14. NMR-based Prostate Cancer Metabolomics Leslie R. Euceda, Maria K. Andersen, May-Britt Tessem, Siver A. Moestue, Maria T. Grinde, and Tone F. Bathen
15. Studies on Steroid Receptor Coactivators in Prostate Cancer
Zoran Culig and Frederic R. Santer
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