Inhalation toxicology
著者
書誌事項
Inhalation toxicology
CRC Press, c2015
3rd ed
- : hbk
大学図書館所蔵 全1件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
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  オランダ
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The lungs provide a significant opportunity for the introduction of both therapeutic and toxic chemicals into the human body. In occupational and domestic environments, hazardous chemicals can enter the body through the lungs via gases, aerosols, and particulates from natural and anthropogenic sources. Fully updated with new research and discoveries since the last edition, Inhalation Toxicology, Third Edition presents contributions from internationally recognized scientists in the academic, commercial/industrial, and governmental sectors. A pragmatic resource for practicing professionals and students, the book comprehensively examines the relationship between the respiratory system and the toxicology of inhaled substances.
Topics include:
Regulatory aspects of exposure and testing
Testing equipment and procedures
Respiratory allergy and irritation of the respiratory tract
Risk assessment
Toxicology theory
Toxicology modeling
Toxic effects of some individual toxicants
New topics in this third edition include collection and characterization of airborne particulate matter, the inhalation toxicology of asbestos fibers and nanoparticles, and the development of lung-on-a-chip technology for predicting in vivo responses. Each chapter concludes with thought-provoking questions and answers, enhancing the book's educational utility.
目次
Collection and Characterization of Particulate Matter Deposition. Nose-Only Aerosol Exposure Systems: Design, Operation, and Performance. Lungs-on-a-Chip. Human Health Risk Assessment of Inhaled Materials. Application of Inhalation Toxicology Concepts to Risk and Consequence Assessments. Time Scaling of Dose and Time to Response: The Toxic Load Exponent. Improper Use of Haber's Law Results in Erroneous Fatality Estimation from Predictive Models. Physiologically Based Kinetic Modeling of Inhalation. Nanomaterial Inhalation Exposure from Nanotechnology-Based Consumer Products. Influence of Physicochemical Properties on the Bioactivity of Carbon Nanotubes/Nanofibers and Metal Oxide Nanoparticles. Inhalation Toxicology of Riot Control Agents. Incapacitating Agents. Exposure to Ammonia. Serpentine and Amphibole Asbestos. Pulmonary Primary Cells Cocultured in a Novel Cell Culture System, the Integrated Discrete Multiple Cell-Type Coculture System (IdMOC): Pulmonary Cytotoxicity of Eight Cigarette Smoke Condensates and Nicotine. Animal Models of Chronic Obstructive Pulmonary Disease (COPD). Toxic Inhalation Injury: Management and Medical Treatment. Transcriptomic Responses to Crystalline Silica Exposure. Mechanisms Involved in the Inhalation Toxicity of Phosgene. Chemical Warfare Agents and Nuclear Weapons. Emergency Response Planning Guidelines. Safety Assessment of Therapeutic Agents Administered by the Respiratory Routes. Index.
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