Data mining for systems biology : methods and protocols

著者

    • Mamitsuka, Hiroshi

書誌事項

Data mining for systems biology : methods and protocols

edited by Hiroshi Mamitsuka

(Methods in molecular biology / John M. Walker, series editor, 1807)(Springer protocols)

Humana Press, c2018

2nd ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This fully updated book collects numerous data mining techniques, reflecting the acceleration and diversity of the development of data-driven approaches to the life sciences. The first half of the volume examines genomics, particularly metagenomics and epigenomics, which promise to deepen our knowledge of genes and genomes, while the second half of the book emphasizes metabolism and the metabolome as well as relevant medicine-oriented subjects. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that is useful for getting optimal results. Authoritative and practical, Data Mining for Systems Biology: Methods and Protocols, Second Edition serves as an ideal resource for researchers of biology and relevant fields, such as medical, pharmaceutical, and agricultural sciences, as well as for the scientists and engineers who are working on developing data-driven techniques, such as databases, data sciences, data mining, visualization systems, and machine learning or artificial intelligence that now are central to the paradigm-altering discoveries being made with a higher frequency.

目次

1. Identifying Bacterial Strains from Sequencing Data Tommi Maklin, Jukka Corander, and Antti Honkela 2. MetaVW: Large-Scale Machine Learning for Metagenomics Sequence Classification Kevin Vervier, Pierre Mahe, and Jean-Philippe Vert 3. Online Interactive Microbial Classification and Geospatial Distributional Analysis Using BioAtlas Jesper Lund, Qihua Tan, and Jan Baumbach 4. Generative Models for Quantification of DNA Modifications Tarmo AEijoe, Richard Bonneau, and Harri Lahdesmaki 5. DiMmer: Discovery of Differentially Methylated Regions in Epigenome-Wide Association Study (EWAS) Data Tobias Frisch, Jonatan Gottcke, Richard Roettger, Qihua Tan, and Jan Baumbach 6. Implementing a Transcription Factor Interaction Prediction System Using the GenoMetric Query Language Stefano Perna, Arif Canakoglu, Pietro Pinoli, Stefano Ceri, and Limsoon Wong 7. Multiple Testing Tool to Detect Combinatorial Effects in Biology Aika Terada and Koji Tsuda 8. SiBIC: A Tool for Generating a Network of Biclusters Captured by Maximal Frequent Itemset Mining Kei-ichiro Takahashi, David A. duVerle, Sohiya Yotsukura, Ichigaku Takigawa, and Hiroshi Mamitsuka 9. Computing and Visualizing Gene Function Similarity and Coherence with NaviGO Ziyun Ding, Qing Wei, and Daisuke Kihara 10. Analyzing Glycan Binding Profiles Using Weighted Multiple Alignment of Trees Kiyoko F. Aoki-Kinoshita 11. Analysis of Fluxomic Experiments with Principal Metabolic Flux Mode Analysis Sahely Bhadra and Juho Rousu 12. Analyzing Tandem Mass Spectra Using the DRIP Toolkit: Training, Searching, and Post-Processing John T. Halloran 13. Sparse Modeling to Analyze Drug-Target Interaction Networks Yoshihiro Yamanishi 14. DrugE-Rank: Predicting Drug-Target Interactions by Learning to Rank Jieyao Deng, Qingjun Yuan, Hiroshi Mamitsuka, and Shanfeng Zhu 15. MeSHLabeler and DeepMeSH: Recent Progress in Large-Scale MeSH Indexing Shengwen Peng, Hiroshi Mamitsuka, and Shanfeng Zhu 16. Disease Gene Classification with Metagraph Representations Sezin Kircali Ata, Yuan Fang, Min Wu, Xiao-Li Li, and Xiaokui Xiao 17. Inferring Antimicrobial Resistance from Pathogen Genomes in KEGG Minoru Kanehisa

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