Biomechanics in oncology

著者

    • Dong, Cheng
    • Zahir, Nastaran
    • Konstantopoulos, Konstantinos

書誌事項

Biomechanics in oncology

Cheng Dong, Nastaran Zahir, Konstantinos Konstantopoulos, editors

(Advances in experimental medicine and biology, v. 1092)

Springer, c2018

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs' role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer

目次

Biomaterials in Mechano-oncology: Means to Tune Materials to Study Cancer.- Traction Force Microscopy for Non-Invasive Imaging of Cell Forces.- Non-Invasive Imaging: Brillouin Confocal Microscopy.- Exposing Cell-itary Confinement: Understanding The Mechanisms Of Confined Single Cell Migration.- Modeling Cell Migration Mechanics.- Engineered models of metastasis with application to study cancer biomechanics.- Microenvironment influences cancer cell mechanics from tumor growth to metastasis.- From Cancer Immunoediting to New Strategies in Cancer Immunotherapy: The Roles of Immune Cells and Mechanics in Oncology.- Biomechanics of the circulating tumor cell microenvironment.- Mechanics of the cell nucleus.- Mechanical Forces in Tumor Angiogenesis.- DNA Mechanics and Topology.- Design of Fiber Networks for Studying Metastatic Invasion.- Extracellular matrix stiffness exists in a feedback loop that drives tumor progression.- Platelet-Based Drug Delivery for Cancer Applications.- The National Cancer Institute Investment in Biomechanics in Oncology Research.

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