Allergic Contact Dermatitis : The Molecular Basis
著者
書誌事項
Allergic Contact Dermatitis : The Molecular Basis
Springer, c1998
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注記
"with a Foreword by R.J.G. Rycroft"--T.p. verso
Includes bibliographical references and index
内容説明・目次
内容説明
Allergic Contact Dermatitis presents all up-to-date chemical and physio-chemical concepts for the study and understanding of allergic contact dermatitis (ACD). The book covers all aspects of ACD - skin penetration and metabolism, identification of sensitizers and hapten-protein interaction, including new concepts of increasing importance such as molecular recognition and quantitative structure-activity relationships. In addition, comprehensive references are provided, making this the most complete available text-book for dermatologists. Allergic Contact Dermatitis reaches an equilibrium between fundamental concepts and clinical applications and thus presents an essential guideline to dermatologists, allergologists, biochemists and toxicologists.
目次
1. Introduction.- 2. Immunological Aspects.- 3. Chemical Basis.- 4. Isolation and Identification of Contact Allergens.- 5. Skin Metabolism.- 6. Hapten-Protein Interactions.- 7. Molecular Basis for the Recognition of Haptens by T Lymphocytes.- 8. Structure-Activity Relationships for Contact Hypersensitivity.- 9. The Practical Approach.
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