Practical guide to ChIP-seq data analysis

著者
    • Mifsud, Borbala
    • Zarnack, Kathi
    • Bardet, Anais F
書誌事項

Practical guide to ChIP-seq data analysis

Borbala Mifsud, Kathi Zarnack, Anaïs F Bardet

(CRC focus, . Focus computational biology series)(A Chapman & Hall book)

CRC Press, c2019

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Chromatin immunoprecipitation sequencing (ChIP-seq), which maps the genome-wide localization patterns of transcription factors and epigenetic marks, is among the most widely used methods in molecular biology. Practical Guide to ChIP-seq Data Analysis will guide readers through the steps of ChIP-seq analysis: from quality control, through peak calling, to downstream analyses. It will help experimental biologists to design their ChIP-seq experiments with the analysis in mind, and to perform the basic analysis steps themselves. It also aims to support bioinformaticians to understand how the data is generated, what the sources of biases are, and which methods are appropriate for different analyses.

目次

Chapter 1 Introduction to ChIP-seq Chapter 2 Getting Started Chapter 3 General Quality Control Chapter 4 Genomic Alignment Chapter 5 ChIP-seq-specific Quality Control Chapter 6 Peak Calling Chapter 7 Data visualisation Chapter 8 Comparative Analysis Chapter 9 Downstream Analyses

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