Practical guide to ChIP-seq data analysis
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Bibliographic Information
Practical guide to ChIP-seq data analysis
（CRC focus, . Focus computational biology series）（A Chapman & Hall book）
CRC Press, c2019
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Includes bibliographical references and index
Description and Table of Contents
Description
Chromatin immunoprecipitation sequencing (ChIP-seq), which maps the genome-wide localization patterns of transcription factors and epigenetic marks, is among the most widely used methods in molecular biology. Practical Guide to ChIP-seq Data Analysis will guide readers through the steps of ChIP-seq analysis: from quality control, through peak calling, to downstream analyses. It will help experimental biologists to design their ChIP-seq experiments with the analysis in mind, and to perform the basic analysis steps themselves. It also aims to support bioinformaticians to understand how the data is generated, what the sources of biases are, and which methods are appropriate for different analyses.
Table of Contents
Chapter 1 Introduction to ChIP-seq
Chapter 2 Getting Started
Chapter 3 General Quality Control
Chapter 4 Genomic Alignment
Chapter 5 ChIP-seq-specific Quality Control
Chapter 6 Peak Calling
Chapter 7 Data visualisation
Chapter 8 Comparative Analysis
Chapter 9 Downstream Analyses
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