Mysteries in muscle contraction : evidence against current dogmas
著者
書誌事項
Mysteries in muscle contraction : evidence against current dogmas
Pan Stanford Publishing, c2018
- : hardcover
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book explores the author's wide-ranging work on muscle research, which spans more than 50 years. It delves into the dogmas of muscle contraction: how the models were constructed and what was overlooked during the process, including their resulting shortcomings. The text stimulates general readers' and researchers' interest, highlights the author's pioneering work on the electron microscopic recording of myosin head power and recovery strokes, and presents a frank discussion on how the original work sometimes tends to be overlooked by competing scientists, who hinder the progress of science.
目次
Historical Background. Dogmas of Huxley-Simmons Model Not Supported Experimentally. New Methods and New Dogmas and Their Shortcomings. The Swinging Lever Arm Hypothesis: A Prominent Current Dogma. Electron Microscopic Recording of ATP-Induced Myosin Head Movement. Evidence against Current Dogmas of Muscle Contraction as Revealed by the Effect of Antibodies to Myosin Head. Electron Microscopic Recording of Myosin Head Power Stroke: Possible Sequence of Actin-Myosin Interaction in Muscle. The Fenn Effect: A fundamental Mystery in Muscle. Load-Dependent Mechanical Efficiency of Myosin Heads. Past History-Dependence of Myosin Head Performance. Mysteries in Unfamiliar Muscle and Motile Systems.
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