Neuroimmune diseases : from cells to the living brain

著者

    • Mitoma, Hiroshi
    • Mario Manto

書誌事項

Neuroimmune diseases : from cells to the living brain

Hiroshi Mitoma, Mario Manto, editors

(Contemporary clinical neuroscience / Ralph Lydic, Helen A. Baghdoyan)

Springer, c2019

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内容説明・目次

内容説明

A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

目次

  • SECTION I. Fundamental pathogenic actions 1Overview of mechanisms underlying neuroimmune diseases Korn T (Germany) 2 Roles of interleukines in neurological autoimmunity Waisman A( Germany) 3 Roles of regulatory T cells in neurological autoimmunity Hafler DA (USA) 4 Immune tolerance triggering neurological autoimmunity Prabhaker BS (USA) 5 Disruption of blood-brain barrier and blood-nerve barrier: a key step in development of immune-mediated neurological diseases Varatharaj A (UK) 6 Pathological mechanisms underlying production of autoantibodies Zenker P (Australia) 7 Significance of autoantibodies: cause or result? Dalmau J (USA), Lanchaster E (USA) 8 Multiple actions of microglia Kettenmann H (Germany) 9 Autoimmune astropathy Bradl M (Australlia) 10 Genetic factors indicating susceptibility to neurological diseases Baranzini SE (USA) SECTION II. Clinical immunology: Pathogenesis, updated diagnostic criteria and novel therapeutic strategies 1 CNS neuroimmune diseases 11 General principles of immunotherapy Vincent A (UK) 12 Multiple sclerosis Brownlee WJ (UK) 13 Neuromyelitis optica: Diagnosis and therapies Biousse V (USA) 14 Atypical inflammatory demyelinating syndrome Hardy TA (Australia) 15 Central nervous system vasculitis Benseler SM (Canada) 16 Neuro-Bechet and Sjogren disease Al-Araji A (UK) 17 Immune-mediated cortical encephalopathy (Limbic encephalitis) Graus F (Spain) 18 Immune-mediated cerebellar ataxias Hadjivassiliou M (UK) 19 Stiff-Person syndrome Balint B (UK) 2 Peripheral neuroimmune diseases 20 Guillain-Barre syndrome Goodfellow JA (UK) 21 Chronic inflammatory demyelinating polyneuropathy: Diagnosis and therapy Said G (France) 22 Immune-mediated disorders of neuro-muscular junctions Gilhus NE (Norway) 23 Myositis Oldroyd A (UK) 3 Systemic neuroimmune diseases 24 Infection-related immune diseases Hadjivassiliou M (UK) 25 Paraneoplastic neurological syndromes
  • Diagnosis and Therapies Honnorat J (France)

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