Chemical sciences in early drug discovery : medicinal chemistry 2.0
著者
書誌事項
Chemical sciences in early drug discovery : medicinal chemistry 2.0
Elsevier, c2018
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.
目次
1. Step 1: Target Identification 2. Step II: Target Validation 3. Step IIIa: Biological Hit Discovery Through High-Throughput Screening (HTS): Random Approaches and Rational Design 4. Step IIIb: The Drug-Like Chemical Diversity Pool: Diverse and Targeted Compound Collections
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