Amino-acid homopolymers occurring in nature
著者
書誌事項
Amino-acid homopolymers occurring in nature
（Microbiology monographs / series ed. Alexander Steinbüchel, v. 15）
Springer, c2010
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Microorganisms are capable of producing a wide variety of biopolymers. Homopolymer peptides, which are made up of only a single type of amino acid, are far less ubiquitous. The only two amino-acid homopolymers known to occur in nature are presented in this volume.
Poly-epsilon-L-lysine is a polycationic peptide and exhibits antimicrobial activity against a wide spectrum of microorganisms. It is both safe and biodegradable and is therefore used as a food preservative in several countries. In addition, there has been great interest in medical and other applications of poly-lysine and its derivatives.
In contrast, poly-gamma-glutamic acid is an unusual anionic polypeptide. It is also water soluble, biodegradable, edible, non-toxic and non-immunogenic and can be chemically modified to introduce various drugs. These features are very useful for pharmaceutical and biomedical applications. Poly-glutamic acid is also a highly attractive as a food ingredient.
目次
Occurrence and Production of Poly-Epsilon-l-Lysine in Microorganisms.- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Biosynthesis.- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Degradation.- Biotechnological Production of Poly-Epsilon-l-Lysine for Food and Medical Applications.- Occurrence and Biosynthetic Mechanism of Poly-Gamma-Glutamic Acid.- Enzymatic Degradation of Poly-Gamma-Glutamic Acid.- Pharmaceutical and Medical Applications of Poly-Gamma-Glutamic Acid.- Food Applications of Poly-Gamma-Glutamic Acid.
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