Paraquat poisoning : mechanisms, prevention, treatment

著者

    • Bismuth, Chantal
    • Hall, Alan H.

書誌事項

Paraquat poisoning : mechanisms, prevention, treatment

edited by Chantal Bismuth, Alan H. Hall

(Drug and chemical toxicology, v. 10)

M. Dekker, c1995

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume offers in-depth coverage of all important aspects of human paraquat poisoning, providing recent information on everything from the basic science of liquid peroxidation, to recent recommendations for prevention, diagnosis, prognosis and treatment. Perspectives from developed and developing countries are given. This work is intended for: medical and clinical toxicologists, organic, medicinal, agricultural and herbicide chemists; poison information specialists; public health, regulatory compliance and risk management officers; sanitarians; industrial hygienists; ecologists; and graduate-level and continuing-education students in these disciplines.

目次

  • History of paraquat intoxication
  • paraquat usage - environmental fate and effects
  • epidemiology of paraquat poisoning
  • paraquat and diquat exposures reported to US poison centers 1983-1992
  • measurement of lipid peroxidation - a critical review
  • the chemistry of paraquat and its radical
  • pathophysiology and biochemical mechanisms of the pulmonary toxicity of paraquat
  • mechanisms of paraquat toxicity and therapeutic implications
  • toxicokinetics of paraquat
  • paraquat ingestion exposure - symptomatology and risk
  • paraquat poisoning by inhalation or skin adsorption
  • genetic, carcinogenic, and reproductive effects of paraquat
  • occupational health and safety considerations in paraquat handling
  • human paraquat toxicology - prognostic factors
  • predictive value of early plasma paraquat concentrations
  • analytical procedures and predictive value of late plasma and urine paraquat concentrations
  • treatment of paraquat poisoning - gastrointestinal decontamination
  • treatment of paraquat poisoning - modification of toxicokinetics
  • treatment of paraquat poisoning
  • paraquat formulation and safety management
  • pulmonary sequelae in paraquat poisoning survivors.

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