Glycan-based cellular communication : techniques for carbohydrate-protein interactions
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書誌事項
Glycan-based cellular communication : techniques for carbohydrate-protein interactions
（ACS symposium series, 1346）
American Chemical Society, c2020
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
Glycan interactions with a variety of glycan binding proteins (GBPs) play a significant role in cell-cell communication, immune evasion, and pathogenic processes. Understanding these interactions is critical to regulating cellular processes and has tremendous therapeutic significance. However, methods to study glycan interactions are relatively limited due to several structural and functional properties of glycans.
This work explores specially adapted methods of study, with advances such as glycan microarrays, glycosylated conductive polymers, Luminex bead-based arrays, metabolic labelling, cell surface engineering, and chemo enzymatic labeling. This volume serves as a valuable tool for researchers and industry workers interested in developing and adapting technologies in the detection of glycan-GBP interactions.
目次
Preface
Chapter 1. Recent Advancements in Arrayed Technologies and Emerging Themes in the Identification of Glycan-Protein Interactions, Eugene Joeh, Zak Vilen, Timothy O'Leary, and Mia L. Huang
Chapter 2. Insights into Antibody-Carbohydrate Recognition from Neoglycoprotein Microarrays, Jeffrey C. Gildersleeve
Chapter 3. Generation of a Heparan Sulfate Mutant Cell Library and Its Application to Determine the Structure-Function Relationship of Heparan Sulfate in Facilitating FGF2-FGFR1 Signaling, John Faulkner, Xuehong Song, and Lianchun Wang
Chapter 4. Polyvalent Glycan-Quantum Dots as Multifunctional Structural Probes for Multivalent Lectin-Carbohydrate Interactions, James Hooper, Yuan Guo, and Dejian Zhou
Chapter 5. Automated Identification of Lectin Fine Specificities from Glycan-Array Data, Zachary Klamer and Brian Haab
Chapter 6. Label-Free Biosensors for Studying Carbohydrate-Protein Interaction, Abdul Rehman, Lei Li, and Xiangqun Zeng
Chapter 7. Sketching the Glycan Hallmark of Intact Cells Using Lectin Microarray, Sheng-Ce Tao and Shumin Zhou
Chapter 8. Methods to Investigate Innate Immune Receptors and Their Carbohydrate-Based Ligands, Siavash Mashayekh, Elizabeth A. D'Ambrosio, and Catherine L. Grimes
Chapter 9. Morphogenesis of the Mammalian Tectorial Membrane: Unveiling the Surface Roles of a Matrix Organizer, Alpha Tecto, Dong-Kyu Kim and Sungjin Park
Chapter 10. Mass Spectrometric Analysis of Protein Glycosylation, He Zhu, Arya Aloor, Cheng Ma, Shukkoor M. Kondengaden, and Peng George Wang
Editors' Biographies
Author Index
Subject Index
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