Targeted nanosystems for therapeutic applications : new concepts, dynamic properties, efficiency, and toxicity

書誌事項

Targeted nanosystems for therapeutic applications : new concepts, dynamic properties, efficiency, and toxicity

Kazuo Sakurai, editor, Marc A. Ilies, editor ; sponsored by the ACS Division of Colloid and Surface Chemistry

(ACS symposium series, 1309)

American Chemical Society, c2019

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注記

Includes bibliographical references and indexes

"This book originates in the symposium with the same title, held at the 254th ACS National Meeting in Washington, DC on August 20-24, 2017."--Pref.

内容説明・目次

内容説明

Despite the potential of nanoparticles in nanomedicine and decades of research, it remains challenging to actively target nanoparticles. Focusing on recent research and development, this book identifies and presents potential new paradigms and ideas to meet practical demands in different biomedical areas. The book reveals new developments and identifies new clinically relevant targets and strategies to increase targeting efficiency and reduce toxicity. Scientists in chemical, biological, pharmaceutical, and clinical roles in academia and the broader industry will find this book interesting.

目次

Preface Chapter 1. Targeted Therapeutic Genome Engineering: Opportunities and Bottlenecks in Medical Translation, Jessica A. Kretzmann, David C. Luther, Marck Norret, Vincent M. Rotello, and K. Swaminathan Iyer Chapter 2. Aerosol Delivery to the Airways Using Cationic Lipid Nanocomplexes in a Perspective of Cystic Fibrosis Treatment, Mathieu Berchel, Paul-Alain Jaffres, Tony Le Gall, and Tristan Montier Chapter 3. Hybrid Nucleic Acid Nanocapsules for Targeted, Enzyme-Specific Drug Delivery and Intracellular Gene Regulation, Joshua J. Santiana, Saketh Gudipati, Alyssa K. Hartmann, and Jessica L. Rouge Chapter 4. A Novel Polysaccharide Carrier for Functional Oligonucleotides: Immunocyte Targeting through ss-Glucan Receptors, Noriko Miyamoto, Shinichi Mochizuki, and Kazuo Sakurai Chapter 5. Thiourea-Functional Bioreducible Poly(amido amine)s in Gene Delivery, M. Rachel Elzes, Guoying Si, Johan F. J. Engbersen, and Jos M. J. Paulusse Chapter 6. Non-Crosslinking Aggregation of DNA-Functionalized Gold Nanoparticles for Gene Diagnosis and Directed Assembly, Guoqing Wang, Yoshitsugu Akiyama, Naoki Kanayama, Tohru Takarada, and Mizuo Maeda Chapter 7. Self-Assembly of Noble Metal-Based Hybrid Nanostructures Using a Combination of Colloidal and Aerosol-Based Approaches, Hung-Li Wang and De-Hao Tsai Chapter 8. Mechanisms of Actively Triggered Drug Delivery from Hard Nanoparticle Carriers, Ajmeeta Sangtani, Megan E. Muroski, and James B. Delehanty Chapter 9. Inclusion Complexes in Drug Delivery and Drug Targeting: Formation, Characterization, and Biological Applications, Rajesh K. K. Sanku, Ozlem O. Karakus, Monica Ilies, and Marc A. Ilies Chapter 10. Drug Delivery to Hypoxic Tumors Targeting Carbonic Anhydrase IX, Ahmed M. Shabana and Marc A. Ilies Chapter 11. Light-Induced Reactive-Oxygen-Species- (ROS-) Mediated Activation of Self-Assembled Nanoplatforms for On-Demand Drug Delivery, Gurusamy Saravanakumar and Won Jong Kim Chapter 12. Redox Polyion Complex Micelle-Based Injectable Hydrogel as Local Reactive Oxygen Species Scavenging Therapeutics, Long Binh Vong and Yukio Nagasaki Chapter 13. Colon-Targeted Delivery Systems for Therapeutic Applications: Drug Release from Multiparticulate, Monolithic Matrix, and Capsule-Filled Delivery Systems, Safa Cyrus Fassihi, Rahmat Talukder, and Reza Fassihi Editors' Biographies Indexes Author Index Subject Index

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