Hidden Markov models : methods and protocols

著者

書誌事項

Hidden Markov models : methods and protocols

edited by David R. Westhead and M.S. Vijayabaskar

(Methods in molecular biology / John M. Walker, series editor, v. 1552)(Springer protocols)

Humana Press, c2017

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume aims to provide a new perspective on the broader usage of Hidden Markov Models (HMMs) in biology. Hidden Markov Models: Methods and Protocols guides readers through chapters on biological systems; ranging from single biomolecule, cellular level, and to organism level and the use of HMMs in unravelling the complex mechanisms that govern these complex systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Hidden Markov Models: Methods and Protocols aims to demonstrate the impact of HMM in biology and inspire new research.

目次

1. Introduction to Hidden Markov Models and its Applications in Biology M S Vijayabaskar 2. HMMs in Protein Fold Classification Christos Lampros, Costas Papaloukas, Themis Exarchos, and Dimitrios I. Fotiadis 3. Application of Hidden Markov Models in Biomolecular Simulations Saurabh Shukla, Zahra Shamsi, Alexander S. Moffett, Balaji Selvam, and Diwakar Shukla 4. Predicting Beta Barrel Transmembrane Proteins using HMMs Georgios N. Tsaousis, Stavros J. Hamodrakas , and Pantelis G. Bagos 5. Predicting Alpha Helical Transmembrane Proteins using HMMs Georgios N. Tsaousis, Margarita C. Theodoropoulou, Stavros J. Hamodrakas, and Pantelis G. Bagos 6. Self-Organizing Hidden Markov Model Map (SOHMMM): Biological Sequence Clustering and Cluster Visualization Christos Ferles, William-Scott Beaufort, and Vanessa Ferle 7. Analyzing Single Molecule FRET Trajectories using HMM Kenji Okamoto 8. Modelling ChIP-seq Data using HMMs Veronica Vinciotti 9. Hidden Markov Models in Bioinformatics: SNV Inference from Next Generation Sequence Jiawen Bian and Xiaobo Zhou 10. Computationally Tractable Multivariate HMM in Genome-wide Mapping Studies Hyungwon Choi, Debashis Ghosh, and Zhaohui Qin 11. Hidden Markov Models in Population Genomics Julien Y. Dutheil 12. Differential Gene Expression (DEX) and Alternative Splicing Events (ASE) for Temporal Dynamic Processes using HMMs and Hierarchical Bayesian Modeling Approaches Sunghee Oh and Seongho Song 13. Finding RNA-Protein Interaction Sites using HMM Tao Wang, Jonghyun Yun, Yang Xie, and Guanghua Xiao 14. Automated Estimation of Mouse Social Behaviours Based on a Hidden Markov Model Toshiya Arakawa, Akira Tanave, Aki Takahashi, Satoshi Kakihara, Tsuyoshi Koide, and Takashi Tsuchiya 15. Modeling Movement Primitives with Hidden Markov Models for Robotic and Biomedical Applications Michelle Karg and Dana Kulic

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