Handbook of pharmaceutical granulation technology

著者

    • Parikh, Dilip M.

書誌事項

Handbook of pharmaceutical granulation technology

edited by Dilip M. Parikh

(Drugs and the pharmaceutical sciences)

CRC Press, 2021

4th ed

  • : hbk

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration, process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more than 50 global subject matter experts who share their years of experience in areas ranging from drug delivery and pharmaceutical technology to advances in nanotechnology. Every pharmaceutical scientist should own a copy of this fourth edition resource. Key Features: Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies

目次

1 Introduction 2 Theory of Granulation: An Engineering Perspective 3 Drug Substance and Excipient Characterization 4 Binders in Pharmaceutical Granulation 5 Excipients and their Attributes in Granulation 6 Spray Drying and Pharmaceutical Applications 7 Emerging Technologies for Particle Engineering 8 Roller Compaction Technology 9 Advances in Wet Granulation of Modern Drugs 10 Fluid Bed Granulation 11 Single Pot Processing 12 Extrusion/Spheronization as a Granulation Technique 13 Continuous Granulation 14 Effervescent Granulation 15 Granulation of Plant Products and Nutraceuticals 16 Granulation Approaches for Modified Release Products 17 Granulation of Poorly Water-Soluble Drugs 18 Granulation and Production Approaches of Orally Disintegrating Tablets 19 Melt Granulation 20 Sizing of Granulation 21 Granulation Characterization 22 Bioavailability and Granule Properties 23 Granulation Process Modeling 24 Scale-Up Considerations in Granulation 25 Advances in Process Controls and End-Point Determination 26 Use of Artificial Intelligence and Expert Systems in Pharmaceutical Applications 27 Regulatory Issues in Granulation: Leading Next Generation Manufacturing

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