RNA editing : methods and protocols

著者

• Picardi, Ernesto
• Pesole, Graziano

書誌事項

RNA editing : methods and protocols

edited by Ernesto Picardi and Graziano Pesole

（Methods in molecular biology / John M. Walker, series editor, 2181）（Springer protocols）

Humana Press, c2021

• : [hardback]

注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume provides an overview about main RNA editing mechanisms, focusing on their functions in physiological as well as pathological conditions. Chapters guide readers through state- of-the art methodologies to investigate RNA editing through wet and dry approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Editing: Methods and Protocols aims to ensure successful results in the further study of this vital field.

目次

1. Substitutional RNA Editing in Plant Organelles Mizuho Ichinos and Mamoru Sugita 2. Computational Detection of Plant RNA Editing Events Alejandro A. Edera and M. Virginia Sanchez-Puerta 3. Discovering RNA Editing Events in Fungi Huiquan Liu and Jin-Rong Xu 4. C-to-U RNA Editing: From Computational Detection to Experimental Validation Taga Lerner, Mitchell Kluesner, Rafail Nikolaos Tasakis, Branden S. Moriarity, F.N. Papavasiliou, and Riccardo Pecori 5. Live Cell Quantification of APOBEC1-mediated RNA Editing: A Comparison of RNA Editing Assays Martina Chieca, Serena Torrini, and Silvestro G. Conticello 6. Adenosine to Inosine RNA Editing Enzyme ADAR and microRNAs Kang Yuting, Dan Ding, and Hisashi Iizasa 7. Quantitative Analysis of Adenosine-to-Inosine RNA Editing Turnee N. Malik, Jean-Philippe Cartailler, and Ronald B. Emeson 8. Discovering A-to-I RNA Editing Through Chemical Methods Masayuki Sakurai, Shunpei Okada, Hiroki Ueda, and Yang Yuxi 9. ALU A-to-I RNA Editing - Millions of Sites and Many Open Questions Amos Schaffer and Erez Y. Levano 10. RNA Editing in Human and Mouse Tissues Harini Srinivasan, Eng Piew Louis Kok, and Meng How Tan 11. Bioinformatics Resources for RNA Editing Maria Angela Diroma, Loredana Ciaccia, Graziano Pesole, and Ernesto Picardi 12. High-throughput Sequencing to Detect DNA-RNA Changes Claudio Lo Giudice, Graziano Pesole, and Ernesto Picardi 13. Detection of A-to-I Hyper-Edited RNA Sequences Roni Cohen-Fultheim and Erez Y. Levanon 14. Proteome Diversification by RNA Editing Eli Eisenberg 15. MicroRNA Editing Detection and Function: A Combined in silico and Experimental Approach for the Identification and Validation of Putative Oncogenic Targets Valentina Tassinari, Valeriana Cesarini, Domenico Alessandro Silvestris, Andrea Scafidi, Lorenzo Cucina, and Angela Gallo 16. RNA Editing in Interferonopathies Loredana Frassinelli, Silvia Galardi, Silvia Anna Ciafre, and Alessandro Michienzi 17. The Role of RNA Editing in the Immune Response Sadeem Ahmad, Xin Mu, and Sun Hur 18. RNA Editing in Neurological and Neurodegenerative Disorders Pedro Henrique Costa Cruz and Yukio Kawahara 19. New Frontiers for Site-directed RNA Editing - Harnessing Endogenous ADARs Tobias Merkle and Thorsten Stafforst

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詳細情報

• NII書誌ID(NCID): BC03770228
• ISBN:
  • 9781071607862
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xv, 352 p.
• 大きさ: 26 cm
• 親書誌ID:
  • BA10794673
  • BA88873632