High throughput screening : methods, techniques and applications

Author(s)
    • Wigglesworth, Mark J.
    • Murray, David C.W.
    • Holdgate, Geoffrey A.
    • Blackett, Carolyn J.
Bibliographic Information

High throughput screening : methods, techniques and applications

Mark J. Wigglesworth ... [et al.], editors

(Recent trends in biotechnology)

Nova Science Publishers, c2020

Search this Book/Journal
Note

Other editors: David C.W. Murray, Geoffrey A. Holdgate, Carolyn J. Blackett

Includes bibliographical references and index

Description and Table of Contents

Description

High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the discovery of pharmaceutical start points. HTS remains one of the most successful approaches, and therefore an important foundation of drug discovery. In High Throughput Screening: Methods, Techniques and Applications, leading industrial and academic experts in screening and drug discovery explain key technologies and methods while demonstrating how they can be applied to successful hit identification. Describing both traditional and emerging methods in detail, this book provides an overview of these methods to the reader that will serve both those new to the field and expert scientists alike. High Throughput Screening: Methods, Techniques and Applications provides readers with an outline of key elements in the areas of assay development, detailed descriptions of a range of both biochemical and cell-based screening methodologies and strategies, as well as highlighting important steps in data analysis. By describing the basic principles of methods commonly used in HTS, High Throughput Screening: Methods, Techniques and Applications provides an illuminating introduction to HTS, capturing established good practice within the field, thereby imparting both the industrial and academic researcher with the knowledge required to work effectively in both today's and the hit identification laboratories of the future.

Table of Contents

PrefaceAssay Development for High Throughput ScreeningApplication of Fluorescence Technologies to High Throughput Screening AssaysLuminescence Technologies for High Throughput Compound ScreeningAcoustic Mist Ionization Mass Spectrometry (AMI-MS) in High Throughput ScreeningHigh Throughput Flow Cytometry: Principles, Practice and ProspectsPerspectives on High Content Imaging as an HTS Technology: Now and in the FutureBiophysical Hit EvaluationCETSA in High Throughput ScreeningDroplet-Based Microfluidics for High Throughput ScreeningEncoded Library Technologies as Screening Platforms for Drug DiscoveryData Analysis in High Throughput ScreeningThe Application of Iterative Screening to Hit IdentificationAbout the EditorsIndex.

by "Nielsen BookData"

Related Books: 1-1 of 1
Details
Page Top