High throughput screening : methods, techniques and applications
著者
書誌事項
High throughput screening : methods, techniques and applications
(Recent trends in biotechnology)
Nova Science Publishers, c2020
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注記
Other editors: David C.W. Murray, Geoffrey A. Holdgate, Carolyn J. Blackett
Includes bibliographical references and index
内容説明・目次
内容説明
High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the discovery of pharmaceutical start points. HTS remains one of the most successful approaches, and therefore an important foundation of drug discovery. In High Throughput Screening: Methods, Techniques and Applications, leading industrial and academic experts in screening and drug discovery explain key technologies and methods while demonstrating how they can be applied to successful hit identification. Describing both traditional and emerging methods in detail, this book provides an overview of these methods to the reader that will serve both those new to the field and expert scientists alike. High Throughput Screening: Methods, Techniques and Applications provides readers with an outline of key elements in the areas of assay development, detailed descriptions of a range of both biochemical and cell-based screening methodologies and strategies, as well as highlighting important steps in data analysis. By describing the basic principles of methods commonly used in HTS, High Throughput Screening: Methods, Techniques and Applications provides an illuminating introduction to HTS, capturing established good practice within the field, thereby imparting both the industrial and academic researcher with the knowledge required to work effectively in both today's and the hit identification laboratories of the future.
目次
PrefaceAssay Development for High Throughput ScreeningApplication of Fluorescence Technologies to High Throughput Screening AssaysLuminescence Technologies for High Throughput Compound ScreeningAcoustic Mist Ionization Mass Spectrometry (AMI-MS) in High Throughput ScreeningHigh Throughput Flow Cytometry: Principles, Practice and ProspectsPerspectives on High Content Imaging as an HTS Technology: Now and in the FutureBiophysical Hit EvaluationCETSA in High Throughput ScreeningDroplet-Based Microfluidics for High Throughput ScreeningEncoded Library Technologies as Screening Platforms for Drug DiscoveryData Analysis in High Throughput ScreeningThe Application of Iterative Screening to Hit IdentificationAbout the EditorsIndex.
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