Computational methods in synthetic biology

著者

    • Marchisio, Mario Andrea

書誌事項

Computational methods in synthetic biology

edited by Mario Andrea Marchisio

(Methods in molecular biology / John M. Walker, series editor, 2189)(Springer protocols)

Humana Press, c2021

2nd ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This second edition book provides complete coverage of the computational approaches currently used in Synthetic Biology. New chapters detail computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Computational Methods in Synthetic Biology, Second Edition aims to feature a broad overview of the research areas that can be met in the area of in silico Synthetic Biology.

目次

1. Using a Design of Experiments Approach to Inform the Design of Hybrid Synthetic Yeast Promoters James Gilman, Valentin Zulkower, and Filippo Menolascina 2. Computational Design of Multiplex Oligonucleotide-Based Assays Michaela Hendling and Ivan Barisic 3. Computational Methods For The Design Of Recombinase Logic Circuits Sarah Guiziou and Jerome Bonnet 4. Modular Modeling Of Genetic Circuits in SBML Level 3 Mario Andrea Marchisio 5. CRISPR-ERA: A Webserver for Guide RNA Design of Gene Editing and Regulation Honglei Liu and Xiaowo Wang 6. iGUIDE Method for CRISPR Off-target Detection Christopher L. Nobles 7. Web-based Base Editing Toolkits: BE-Designer and BE-Analyzer Gue-Ho Hwang and Sangsu Bae 8. Synthetic Gene Circuit Analysis and Optimization Irene Otero-Muras and Julio R. Banga 9. Monitoring Single S. cerevisiae Cells with Multi-Frequency Electrical Impedance Spectroscopy in an Electrode-integrated Microfluidic Device Zhen Zhu, Yangye Geng, and Yingying Wang 10. Construction of Protein Expression Network Nor Afiqah-Aleng and Zeti-Azura Mohamed-Hussein 11. Systems-theoretic Approaches to Design Biological Networks with Desired Functionalities Priyan Bhattacharya, Karthik Raman, and Arun K. Tangirala 12. A Deterministic Compartmental Modeling Framework for Disease Transmission King James B. Villasin, Eva M. Rodriguez, and Angelyn R. Lao 13. Computer Aided Assembly and Verification of Synthetic Chromosomes Giovanni Stracquadanio and Valentin Zulkower 14. Minimal Genome Design Algorithms using Whole-Cell Models Joshua Rees-Garbutt, Oliver Chalkley, Claire Grierson, and Lucia Marucci 15. Tn-Core: Functionally Interpreting Transposon-Sequencing Data with Metabolic Network Analysis George C diCenzo, Marco Galardini, and Marco Fondi 16. Genome-scale Metabolic Modeling of Escherichia coli and its Chassis Design for Synthetic Biology Applications Bashir Sajo Mienda and Andreas Drager 17. A Systems Bioinformatics Approach to Interconnect Biological Pathways George Minadakis and George M. Spyrou

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詳細情報

  • NII書誌ID(NCID)
    BC04618477
  • ISBN
    • 9781071608210
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    New York, N.Y.
  • ページ数/冊数
    x, 255 p.
  • 大きさ
    26 cm
  • 親書誌ID
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