Advances in membrane proteins : building, signaling and malfunction
著者
書誌事項
Advances in membrane proteins : building, signaling and malfunction
Springer, 2019
- : [pbk]
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注記
Includes bibliographical references
収録内容
- Lipid homeostasis on cell membrane / Xian-Cheng Jiang
- A historical perspective of G protein-coupled receptor structural biology / Yang Chen, Ying Xia, and Yu Cao
- Membrane proteins as targets for biological drugs / Vanita D. Sood and Alec W. Gross
- Cell adhesion molecules / Xiajing Tong and Yan Zou
- The biosynthesis and folding of oily peptide chains / Kai Li and Shi-Qing Cai
- Mechanism of quality control of nascent membrane proteins / Zai-Rong Zhang
内容説明・目次
内容説明
This book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins' formation, signaling and malfunctions. It covers a number of important membrane proteins including receptors, cell adhesion molecules, single-transmembrane proteins and viral membrane proteins, and discusses their structures, functions, related diseases, and roles in drug discovery in detail.
In turn, the book elucidates the lifecycle of membrane proteins, including their synthesis and facilitated folding process, as well as QC procedures for their production. Additional topics include fundamental concepts, the latest findings, and critical puzzles yet to be solved. Given its scope, the book will appeal to a broad readership in the field of membrane structural and functional biology. Junior scientists can use it as an introduction to the field, while advanced scientists will find a broader view of the field beyond their area of specialization.
目次
1. Cell adhesion molecules and development.- 2. Receptors and signal transduction.- 3. Single-transmembrane proteins and antibody drugs.- 4. Viral membrane proteins.- 5. Biosynthesis and folding of oily peptide chains.- 6. Quality control in producing membrane proteins.
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